MR1 antibody
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- Target See all MR1 Antibodies
- MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
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Reactivity
- Human, Mouse, Rat
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This MR1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Flow Cytometry (FACS)
- Cross-Reactivity
- Cow (Bovine)
- No Cross-Reactivity
- Mouse (Murine)
- Purification
- The antibody was purified by affinity chromatography.
- Clone
- 26-5
- Isotype
- IgG2a kappa
- Top Product
- Discover our top product MR1 Primary Antibody
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anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 201-300) antibody
MR1 Reactivity: Human ELISA, WB, IF Host: Mouse Monoclonal 5B5 unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 312-341), (C-Term) antibodyMR1 Reactivity: Human WB Host: Rabbit Polyclonal RB37199 unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 150-253) antibodyMR1 Reactivity: Human ELISA, WB, IHC, IF Host: Rabbit Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 20-260) antibodyMR1 Reactivity: Human WB, IF Host: Rabbit Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 150-253) antibodyMR1 Reactivity: Human, Mouse ELISA, WB, IHC, IF/ICC Host: Rabbit Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 20-260) antibodyMR1 Reactivity: Human ELISA, IHC Host: Rabbit Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) (AA 201-300) antibodyMR1 Reactivity: Human ELISA, WB Host: Mouse Polyclonal unconjugated
anti-Major Histocompatibility Complex, Class I-Related (MR1) antibodyMR1 Reactivity: Chicken WB, IHC, FACS, IP Host: Mouse Monoclonal F21-2 unconjugated
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Concentration
- 0.5 mg/mL
- Buffer
- Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C
- Storage Comment
- The antibody solution should be stored undiluted between 2°C and 8°C.
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- Target
- MR1 (Major Histocompatibility Complex, Class I-Related (MR1))
- Alternative Name
- MR1 (MR1 Products)
- Synonyms
- YFV antibody, hlals antibody, MGC154362 antibody, MR1 antibody, DKFZp468C1823 antibody, HLALS antibody, H2ls antibody, Hlals antibody, MHC class I antigen YF5 antibody, major histocompatibility complex, class I-related antibody, major histocompatibility complex, class I-related L homeolog antibody, YF5 antibody, MR1 antibody, mr1.L antibody, mr1 antibody, Mr1 antibody
- Background
- MHC-related protein 1, also known as MR1, is a nonclassical MHC class I molecule highly conserved in mammals, particularly in its α1/α2 domains. MR1 is required for the development and expansion of the mucosal-associated invariant T (MAIT) cells. The transcripts for MR1 are ubiquitously expressed, but its expression on the cell surface seems to be ligand-dependent. MR1 is involved in the presentation of vitamin-derived compounds from bacterial biosynthetic pathways.
- Pathways
- Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Cancer Immune Checkpoints
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