PAX9 antibody

Catalog No. ABIN2665320

Product Details anti-PAX9 Antibody

Target: PAX9 (Paired Box 9 (PAX9))

Reactivity: Human, Mouse

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX9 antibody is un-conjugated

Application: Multiplex Assay (MA)

Purification: The antibody was purified by affinity chromatography.

Clone: 14D10A24

Isotype: IgG2a kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Phosphate-buffered solution, pH 7.2, containing 0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: The antibody solution should be stored undiluted between 2°C and 8°C.

Target Details for PAX9

Target: PAX9 (Paired Box 9 (PAX9))

Alternative Name: PAX9 (PAX9 Products)

Synonyms: STHAG3 antibody, ChPax9 antibody, PAX-9 antibody, Pax-9 antibody, xpax9 antibody, xpax-9 antibody, paired box 9 antibody, paired box 9 L homeolog antibody, PAX9 antibody, pax9 antibody, Pax9 antibody, pax9.L antibody

Background: PAX9 is a transcription factor belonging to the PAX family, which is composed of nine members defined by the presence of a paired box domain responsible for DNA binding. PAX9 is expressed at the E10 stage and downregulated at the bell stage. It is controlled by Fgf/Bmp signaling and plays an essential role in tooth development. PAX9 deficient mice fail to form teeth and show developmental arrest at the bud stage. In humans, heterozygous mutation in PAX9 is associate with tooth agenesis. These findings support the role of PAX9 in tooth development.