HDAC5 antibody (AA 572-587)

Catalog No. ABIN2668266

Product Details anti-HDAC5 Antibody

Target: HDAC5 (Histone Deacetylase 5 (HDAC5))

Binding Specificity: AA 572-587

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HDAC5 antibody is un-conjugated

Application: Western Blotting (WB), Chromatin Immunoprecipitation (ChIP)

Purification: Affinity Purified

Immunogen: This HDAC5 antibody was raised against a synthetic peptide corresponding to amino acid residues 572-587 of human HDAC5.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 μg/μL

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice:

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage: -80 °C

Storage Comment: Antibodies in solution can be stored at -80 °C for 2 years.

Expiry Date: 6 months

References for anti-HDAC5 antibody (ABIN2668266)

Ow, Palanichamy Kala, Rao, Choi, Bharathy, Taneja: "G9a inhibits MEF2C activity to control sarcomere assembly." in: Scientific reports, Vol. 6, pp. 34163, (2016) (PubMed).

Zhao, Yue, Zhu, Du: "AMP-activated protein kinase regulates beta-catenin transcription via histone deacetylase 5." in: The Journal of biological chemistry, Vol. 286, Issue 18, pp. 16426-34, (2011) (PubMed).

Keedy, Archin, Gates, Espeseth, Hazuda, Margolis: "A limited group of class I histone deacetylases acts to repress human immunodeficiency virus type 1 expression." in: Journal of virology, Vol. 83, Issue 10, pp. 4749-56, (2009) (PubMed).

Basile, Mantovani, Imbriano: "DNA damage promotes histone deacetylase 4 nuclear localization and repression of G2/M promoters, via p53 C-terminal lysines." in: The Journal of biological chemistry, Vol. 281, Issue 4, pp. 2347-57, (2006) (PubMed).

Imbriano, Gurtner, Cocchiarella, Di Agostino, Basile, Gostissa, Dobbelstein, Del Sal, Piaggio, Mantovani: "Direct p53 transcriptional repression: in vivo analysis of CCAAT-containing G2/M promoters." in: Molecular and cellular biology, Vol. 25, Issue 9, pp. 3737-51, (2005) (PubMed).

Target Details for HDAC5

Target: HDAC5 (Histone Deacetylase 5 (HDAC5))

Alternative Name: HDAC5 (HDAC5 Products)

Synonyms: HD5 antibody, NY-CO-9 antibody, AI426555 antibody, Hdac4 antibody, mHDA1 antibody, mKIAA0600 antibody, ATHDA5 antibody, HDA5 antibody, MAF19.7 antibody, MAF19_7 antibody, histone deacetylase 5 antibody, histone deacetylase 5 antibody, HDAC5 antibody, Hdac5 antibody, HDA05 antibody, hdac5 antibody

Molecular Weight: 120 kDa

Gene ID: 10014

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development, Monocarboxylic Acid Catabolic Process