HIPK2 antibody (Homeodomain Interacting Protein Kinase 2) (AA 898-1051)

Details for Product anti-HIPK2 Antibody No. ABIN2668288, Supplier: Log in to see
Antigen
  • HIPK2
  • cb1009
  • si:dkey-16j24.2
  • si:dkey-239k7.1
  • wu:fk56d12
  • pro0593
  • MGC146781
  • PRO0593
  • 1110014O20Rik
  • B230339E18Rik
  • Stank
  • PKM
  • homeodomain interacting protein kinase 2
  • serine/threonine protein kinase
  • HIPK2
  • hipk2
  • Hipk2
Alternatives
anti-Human HIPK2 antibody for Immunohistochemistry
Epitope
AA 898-1051
26
17
13
10
7
4
3
3
3
2
1
1
1
1
1
Reactivity
Human
98
12
8
3
2
2
2
2
2
1
1
1
1
Host
Mouse
86
12
Clonality
Monoclonal
Conjugate
This HIPK2 antibody is un-conjugated
8
8
8
8
8
4
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
64
61
35
16
14
4
3
2
2
1
Options
Supplier
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Immunogen This HIPK2 antibody was raised against a recombinant protein including amino acids 898-1051 of mouse HIPK2.
Isotype IgG
Purification Protein G Chromatography
Alternative Name HIPK2 (HIPK2 Antibody Abstract)
Background HIPK2 (Homeodomain Interacting Protein Kinase 2) is a serine/threonine kinase present in the nucleus that interacts with homeodomain transcription factors and acts as a co-repressor of transcription. It inhibits cell growth, as well as promotes apoptosis through the phosphorylation and subsequent degradation of the anti-apoptotic factor CTBP1. HIPK2 also phosphorylates CBX4 upon DNA damage and promotes its E3 SUMO-protein ligase activity.
Molecular Weight 130 kDa
Gene ID 28996
Research Area Chromatin and Nuclear Signaling, Transcription Factors, DNA/RNA, Apoptosis/Necrosis
Pathways Cell Division Cycle
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1 μg/μL
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice

Avoid repeated freeze/thaw cycles and keep on ice when not in storage.

Storage -20 °C
Storage Comment Antibodies in solution can be stored at -20 °C for 2 years.
Expiry Date 6 months
Product cited in: Isono, Nemoto, Li, Takada, Suzuki, Katsuki, Nakagawara, Koseki: "Overlapping roles for homeodomain-interacting protein kinases hipk1 and hipk2 in the mediation of cell growth in response to morphogenetic and genotoxic signals." in: Molecular and cellular biology, Vol. 26, Issue 7, pp. 2758-71, 2006 (PubMed).

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