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Dystrophin antibody (DMD)

Details for Product anti-DMD Antibody No. ABIN267904, Supplier: Log in to see
Antigen
  • DMD
  • Dmd
  • MGC83347
  • DKFZp459C1629
  • dmd
  • MGC79631
  • DKFZp468A1620
  • Dp71
  • cb664
  • zfDYS
  • im:6911785
  • zgc:110165
  • CG17750
  • CG31175
  • CG34157
  • CG7240
  • CG7243
  • CG7344
  • DLP
  • DLP1
  • DLP186
  • DLP2
  • DLP3
  • DmDLP
  • DmDYS
  • Dmel\\CG34157
  • Dp117
  • Dp186
  • Dp205
  • GI3046716
  • IDLP
  • det
  • dmDLP
  • dmDp186
  • dmDys
  • dys
  • BMD
  • CMD3B
  • DXS142
  • DXS164
  • DXS206
  • DXS230
  • DXS239
  • DXS268
  • DXS269
  • DXS270
  • DXS272
  • DNADMD1
  • RATDMD
  • DXSmh7
  • DXSmh9
  • Dp427
  • mdx
  • pke
  • dystrophin
  • Dystrophin
  • dystrophin, muscular dystrophy
  • DMD
  • Dmd
  • dmd
  • Dys
Reactivity
Fish, Human, Mouse (Murine), Rat (Rattus)
94
62
61
19
9
6
2
1
Host
Mouse
63
39
Clonality (Clone)
Monoclonal ()
Conjugate
This Dystrophin antibody is un-conjugated
4
3
2
2
1
1
1
1
1
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Microarray (MA), ELISA
53
31
31
23
14
13
10
6
4
3
2
1
1
Options
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Immunogen Fusion protein, corresponding to amino acids 3200-3684 of Human Dystrophin.
Clone MANDRA1
Isotype IgG1
Specificity The antibody recognizes an epitope located on the 128 amino acids at the end of the C-terminal domain of the human dystrophin molecule (amino acid residues 3558-3684).
Purification Unpurified
Alternative Name Dystrophin (DMD Antibody Abstract)
Background Gene Symbol: DMD
Gene ID 1756
Research Area Stem Cells, Extracellular Matrix, Microfilaments, Cytoskeleton
Application Notes ELISA 1:100-1:2000, Immunocytochemistry/Immunofluorescence 1:100, MicroarrayELISA: See Nyugen thi Man et al (1992) and Morris G.E et al (1993) IF: Use freshly dissected and frozen human or animal muscle tissue. Immunohistochemical staining of muscle tissue results in a clear labeling confined to the periphery (plasma membrane) of normal striated muscle fibers.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer Ascites
Buffer contains: 15 mM Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Product cited in: Annese, Corsi, Ruggieri, Tamma, Marinaccio, Picocci, Errede, Specchia, De Luca, Frassanito, Desantis, Vacca, Ribatti, Nico: "Isolation and characterization of neural stem cells from dystrophic mdx mouse." in: Experimental cell research, Vol. 343, Issue 2, pp. 190-207, 2016 (PubMed). (Sample species: Mouse (Murine)). Further details: Immunocytochemistry,Immunofluorescence

Nguyen, Ginjaar, van Ommen, Morris: "Monoclonal antibodies for dystrophin analysis. Epitope mapping and improved binding to SDS-treated muscle sections." in: The Biochemical journal, Vol. 288 ( Pt 2), pp. 663-8, 1993 (PubMed).

Morris, Ellis, Nguyen: "A quantitative ELISA for dystrophin." in: Journal of immunological methods, Vol. 161, Issue 1, pp. 23-8, 1993 (PubMed).

Background publications Gussoni, Pavlath, Lanctot, Sharma, Miller, Steinman, Blau: "Normal dystrophin transcripts detected in Duchenne muscular dystrophy patients after myoblast transplantation." in: Nature, Vol. 356, Issue 6368, pp. 435-8, 1992 (PubMed).

Lederfein, Levy, Augier, Mornet, Morris, Fuchs, Yaffe, Nudel: "A 71-kilodalton protein is a major product of the Duchenne muscular dystrophy gene in brain and other nonmuscle tissues." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 12, pp. 5346-50, 1992 (PubMed).

Hugnot, Gilgenkrantz, Vincent, Chafey, Morris, Monaco, Berwald-Netter, Koulakoff, Kaplan, Kahn: "Distal transcript of the dystrophin gene initiated from an alternative first exon and encoding a 75-kDa protein widely distributed in nonmuscle tissues." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 89, Issue 16, pp. 7506-10, 1992 (PubMed).

Ellis, Man, Morris, Ginjaar, Moorman, van Ommen: "Specificity of dystrophin analysis improved with monoclonal antibodies." in: Lancet, Vol. 336, Issue 8719, pp. 881-2, 1990 (PubMed).

Nguyen thi Man, Cartwright, Morris, Love, Bloomfield, Davies: "Monoclonal antibodies against defined regions of the muscular dystrophy protein, dystrophin." in: FEBS letters, Vol. 262, Issue 2, pp. 237-40, 1990 (PubMed).