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Interleukin 15 (IL15) antibody

Details for Product No. ABIN268331
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Antigen
Reactivity
Mouse (Murine)
(105), (53), (29), (3), (3), (2), (1), (1), (1)
Host
Rabbit
(95), (46), (5), (5), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(16), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(106), (96), (19), (16), (12), (12), (11), (10), (10), (10), (7), (5), (4), (3), (2), (2), (2), (1)
Pubmed 4 references available
Quantity 0.1 mg
Shipping to United States (Change)
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Catalog No. ABIN268331
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Immunogen Recombinant full length protein (Mouse). Expressed in E. coli.
Isotype IgG
Specificity IL-15
Cross-Reactivity (Details) Not yet tested in other species.
Purification IgG purified
Alternative Name Interleukin-15 / IL15
Background IL-15 (14-15 kD) is a member of the four alpha-helical bundle family of cytokines. It isvery similar to IL-2, except that IL-15 has an IL-15 alpha receptor subunit. IL-15 plays animportant role in the growth and differentiation of T and B lymphocytes, natural killercells, macrophages, and monocytes as well as activation of a number of importantintracellular signaling molecules. This implies that IL-15 could be essential for theimmune responses, allograft rejection, and the pathogenesis of autoimmune diseases. Alternate Names: anti-IL 15 antibody, anti-interleukin 15 antibody, anti-MGC9721 antibody.
Gene Symbol: IL15
Gene ID 3600
Application Notes WB: Use at a dilution of 1/1000-1/5000. Not tested in other applications. Optimal dilutions/concentrations should be determined by the end user.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
General Cosman, Kumaki, Ahdieh et al.: "Interleukin 15 and its receptor." in: Ciba Foundation symposium, Vol. 195, pp. 221-9; discussion 229-33, 1996 (PubMed).

Kennedy, Park: "Characterization of interleukin-15 (IL-15) and the IL-15 receptor complex." in: Journal of clinical immunology, Vol. 16, Issue 3, pp. 134-43, 1997 (PubMed).

Waldmann, Tagaya, Bamford: "Interleukin-2, interleukin-15, and their receptors." in: International reviews of immunology, Vol. 16, Issue 3-4, pp. 205-26, 1998 (PubMed).

Watkins, Egilmez, Suttles et al.: "IL-12 rapidly alters the functional profile of tumor-associated and tumor-infiltrating macrophages in vitro and in vivo." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 178, Issue 3, pp. 1357-62, 2007 (PubMed).

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