Search, Find and Buy Antibodies, ELISA Kits and Proteins.
Loading Loading
Add to Basket
Order hotline:
phone +1 404 474 4654
fax +1 888 205 9894 (TF)
Details for Product No. ABIN268762

Leucine-Rich Repeat Kinase 2 (LRRK2) antibody

Request
Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms PARK8, RIPK7, ROCO2, AURA17, DARDARIN, Gm927, cI-46, AW561911, 4921513O20Rik, 9330188B09Rik, D630001M17Rik, LRRK2
Reactivity
»Alternatives Human
Host
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunoelectron Microscopy (IEM), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), ELISA, Western Blotting (WB)
Pubmed 2 references available
Catalog no. ABIN268762
Quantity 0.1 mg
Price
Contact our Customer Service for availability and price in your country.
Shipping to
Immunogen Synthetic peptide CELAEKMRRTSV, representing the near the C- Terminus of thehuman protein sequence according to XP_058513. Reference Sequence: XP_058513.
Isotype IgG
Specificity Species Reactivity: Human. Other species not tested.
Cross-Reactivity Human
Purification Affinity Purified
Alternative Name PARK8 / LRRK2
Background This gene is a member of the leucine-rich repeat kinase family and encodes a proteinwith an ankryin repeat region, a leucine-rich repeat (LRR) domain, a kinase domain, aDFG-like motif, a RAS domain, a GTPase domain, a MLK-like domain, and a WD40domain. The protein is present largely in the cytoplasm but also associates with themitochondrial outer membrane. Mutations in this gene have been associated withParkinson disease-8. Alternate Names: anti-LRRK2 antibody, anti-PARK8 antibody, anti-ROCO2 antibody, anti-FLJ45829antibody, anti-DKFZp434H2111 antibody, anti-leucine-rich repeat kinase 2 antibody,anti-dardarin antibody, anti-Parkinson disease (autosomal dominant) 8 antibody.
Gene ID 120892
NCBI Accession XP_058513
Application Notes Suggested working dilutions: ELISA 1:64000,Western Blot
Restrictions For Research Use only
Concentration 0.5 mg/ml
Buffer Tris-saline containing 0.02% Na azide [pH7.3] with 0.5% BSA
Preservative Sodium azide
Storage -20 °C
Paisán-Ruíz, Jain, Evans et al.: "Cloning of the gene containing mutations that cause PARK8-linked Parkinson's disease." in: Neuron, Vol. 44, Issue 4, pp. 595-600, 2004 (PubMed).

Alegre-Abarrategui, Ansorge, Esiri et al.: "LRRK2 is a component of granular alpha-synuclein pathology in the brainstem of Parkinson's disease." in: Neuropathology and applied neurobiology, Vol. 34, Issue 3, pp. 272-83, 2008 (PubMed).

Alternatives for antigen "Leucine-Rich Repeat Kinase 2 (LRRK2)", type "Antibodies"
Hosts (122), (49), (6), (4)
Reactivities (158), (92), (74), (40), (15), (13), (2)
Applications (144), (48), (46), (43), (39), (24), (20), (18), (17), (8), (2), (1), (1), (1), (1)
Conjugates (9), (9), (6), (4), (3), (3), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Epitopes (32), (20), (18), (18), (12), (12), (8), (6), (5), (4), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Beacon