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Details for Product No. ABIN268872

Apolipoprotein A-V (APOA5) antibody

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Antigen
Synonyms RAP3, Apoav, 1300007O05Rik, APOAV, apo-AV, apoA-V, APOA5, MGC140487, rap3, apoav, apoa-v
Reactivity
»Alternatives Human
Host
»Alternatives Mouse
Clonality (Clone) Monoclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives ELISA
Pubmed 1 reference available
Catalog no. ABIN268872
Quantity 25 µL
Price
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Immunogen Ni-NTA purified full length recombinant human APOA5 expressed in E. Coli strain BL21(DE3).
Clone 4H8H8E2
Isotype IgG1
Specificity Species Reactivity: Reacts with human. 83% sequence identity with Bovine, 79% sequence identity withRat, 78% sequence identity with Mouse proteins. Theoretical Molecular Weight: 41 kDa.
Cross-Reactivity Human
Alternative Name Apolipoprotein A V (ApoA V)
Background Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serumtriglyceride concentrations. An ApoA5 mouse knock-out model produced anapproximately four fold increase in serum triglycerides, whereas a knock-in model withhuman ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. Inaddition, peroxisome proliferator-activated receptor-4 (PPAR-alpha) agonists, which areused clinically to lower serum triglyceride concentrations, cause increased ApoA5mRNA expression. Recently, it was demonstrated that ApoA5 ispresent in human serum detected by polyclonal antibodies against both the NH2 andCOOH termini, although at much lower concentration than other apolipoproteins. Alternate Names: anti-Apo-A5 antibody, anti-ApoA5 antibody, anti-Apolipoprotein A5 antibody, anti-ApoA-V antibody, anti-Apolipoprotein A-V antibody, anti-ApoA-V antibody,anti-Apolipoprotein A V antibody. Related Diseases: Coronary Artery Disease, Hypertriglyceridemia
Gene ID 116519
Research Area Metabolism
Restrictions For Research Use only
Pennacchio, Olivier, Hubacek et al.: "An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing." in: Science (New York, N.Y.), Vol. 294, Issue 5540, pp. 169-73, 2001 (PubMed).

Alternatives for antigen "Apolipoprotein A-V (APOA5)", type "Antibodies"
Hosts (63), (37), (5)
Reactivities (100), (13), (13), (12), (9)
Applications (82), (75), (10), (7), (7), (5), (2), (1)
Conjugates (5), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (11), (11), (3), (2), (1)
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