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Apolipoprotein A-V (APOA5) antibody

Antigen

Apolipoprotein A-V (APOA5)
Synonyms RAP3, Apoav, 1300007O05Rik, APOAV, APOA-V, MGC126836, MGC126838, MGC108612, APOA5, MGC140487, rap3, apoav, apoa-v
Clonality Monoclonal (4H8H8E2)
Host
Alternatives

Mouse
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives ELISA
1 reference available
Catalog no. ABIN268872
Quantity 25 µl  (Variants)
Price Product not available in this region.
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Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name Apolipoprotein A V (ApoA V)
Gene ID 116519
Immunogen Ni-NTA purified full length recombinant human APOA5 expressed in E. Coli strain BL21(DE3).
Cross-Reactivity Human
Isotype IgG1
Clone 4H8H8E2
Description Apolipoprotein A5 (ApoA5) is fast gaining attention as a key regulator of serumtriglyceride concentrations. An ApoA5 mouse knock-out model produced anapproximately four fold increase in serum triglycerides, whereas a knock-in model withhuman ApoA5 produced 50-70% lower concentrations of mouse serum triglycerides. Inaddition, peroxisome proliferator-activated receptor-4 (PPAR-alpha) agonists, which areused clinically to lower serum triglyceride concentrations, cause increased ApoA5mRNA expression. Recently, it was demonstrated that ApoA5 ispresent in human serum detected by polyclonal antibodies against both the NH2 andCOOH termini, although at much lower concentration than other apolipoproteins. Alternate Names: anti-Apo-A5 antibody, anti-ApoA5 antibody, anti-Apolipoprotein A5 antibody, anti-ApoA-V antibody, anti-Apolipoprotein A-V antibody, anti-ApoA-V antibody,anti-Apolipoprotein A V antibody. Related Diseases: Coronary Artery Disease, Hypertriglyceridemia
Specificity Species Reactivity: Reacts with human. 83% sequence identity with Bovine, 79% sequence identity withRat, 78% sequence identity with Mouse proteins. Theoretical Molecular Weight: 41 kDa.

Application Details
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Storage Aliquot and store at -20C or -80C. Avoid freeze-thaw cycles.
Research Area Metabolism
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Pennacchio, Olivier, Hubacek et al.: "An apolipoprotein influencing triglycerides in humans and mice revealed by comparative sequencing." in: Science (New York, N.Y.), Vol. 294, Issue 5540, pp. 169-73, 2001 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Apolipoprotein A-V (APOA5)", type "Antibodies"
Hosts Rabbit (33), Mouse (24), Goat (4)
Reactivities Human (58), Rat (Rattus) (21), Mouse (Murine) (20), Dog (Canine) (18), Horse (Equine) (18), Chicken (5)
Applications Western Blotting (WB) (41), ELISA (38), Immunofluorescence (IF) (16), Immunohistochemistry (IHC) (6), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (5), Immunohistochemistry (Formalin-fixed Sections) (IHC (f)) (3), Immunocytochemistry (ICC) (2), Immunoprecipitation (IP) (2), Immunoelectron Microscopy (IEM) (1), Immunohistochemistry (Frozen Sections) (IHC (fro)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), Biotin (1), Cy3 (1), Cy5 (1), Cy5.5 (1), Cy7 (1), FITC (1), Gold (1), HRP (1), PE (1), PE,Cy3 (1), PE,Cy5 (1), PE,Cy5.5 (1), PE,Cy7 (1)
Epitopes C-Term (6), N-Term (6)