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FCER2 antibody

FCER2 Reactivity: Human FACS, WB, IHC (fro) Host: Mouse Monoclonal M unconjugated
Catalog No. ABIN2689105
  • Target See all FCER2 Antibodies
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Reactivity
    • 98
    • 50
    • 11
    Human
    Host
    • 57
    • 47
    • 16
    Mouse
    Clonality
    • 76
    • 42
    • 2
    Monoclonal
    Conjugate
    • 57
    • 16
    • 10
    • 8
    • 5
    • 4
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This FCER2 antibody is un-conjugated
    Application
    • 72
    • 52
    • 33
    • 20
    • 13
    • 10
    • 10
    • 8
    • 5
    • 5
    • 2
    • 1
    • 1
    Flow Cytometry (FACS), Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))
    Brand
    BD Pharmingen™
    Characteristics
    The M-L233 antibody reacts with the low affinity receptor for human IgE, FcεRII/CD23. CD23 is a type II membrane protein which can be expressed by B cells, monocytes, macrophages, eosinophils, platelets, and dendritic cells. CD23 can mediate IgE-dependent cytotoxicity and phagocytosis by macrophages and eosinophils. Soluble CD23 (sCD23) can be released by CD23+ cells as a result of proteolytic cleavage of membrane CD23. Larger fragments of sCD23 (e.g., 37-25 kDa) retain their IgE-binding capacity whereas smaller fragments (i.e., ≤ 12 kDa) do not. Soluble CD23 may have immunoregulatory effects on the growth and differentiation of B cells and other cell types. Profile of peripheral blood lymphocytes analyzed on a FACScan

    BD Pharmingen™ Purified Mouse Anti-Human CD23 - Purified - Clone M-L233 - Isotype Mouse IgG1, κ - Reactivity Hu - 0.5 mg
    Purification
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Clone
    M
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product FCER2 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Concentration
    0.5 mg/mL
    Buffer
    Aqueous buffered solution containing ≤0.09 % sodium azide.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store undiluted at 4°C.
  • Saeland, Duvert, Moreau, Banchereau: "Human B cell precursors proliferate and express CD23 after CD40 ligation." in: The Journal of experimental medicine, Vol. 178, Issue 1, pp. 113-20, (1993) (PubMed).

    Delespesse, Hofstetter, Sarfati: "Low-affinity receptor for IgE (FcERII, CD23) and its soluble fragments." in: International archives of allergy and applied immunology, Vol. 90 Suppl 1, pp. 41-4, (1990) (PubMed).

    Gordon, Millsum, Flores-Romo, Gillis: "Regulation of resting and cycling human B lymphocytes via surface IgM and the accessory molecules interleukin-4, CD23 and CD40." in: Immunology, Vol. 68, Issue 4, pp. 526-31, (1990) (PubMed).

  • Target
    FCER2 (Fc Fragment of IgE, Low Affinity II, Receptor For (CD23) (FCER2))
    Alternative Name
    CD23 (FCER2 Products)
    Synonyms
    BLAST-2 antibody, CD23 antibody, CD23A antibody, CLEC4J antibody, FCE2 antibody, IGEBF antibody, Fcer2a antibody, Fc fragment of IgE receptor II antibody, FCER2 antibody, Fcer2 antibody
    Pathways
    Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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