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Survivin antibody (BIRC5) (HRP)

Details for Product anti-BIRC5 Antibody No. ABIN268915, Supplier: Log in to see
Antigen
  • AAC-11
  • api4
  • Api4
  • BIR1
  • bir5a
  • birc5
  • BIRC5
  • epr-1
  • LOC398389
  • SIX
  • Su1
  • Su2
  • Survivin
  • survivin
  • Survivin1
  • survivin40
  • svv1
  • svv2
  • TIAP
  • XBIR1
  • xsurv
  • xSurvivin
  • xSurvivin1
  • xSurvivin2
Reactivity
Cat (Feline), Dog (Canine), Guinea Pig, Hamster, Human, Mouse (Murine), Rat (Rattus)
355
129
127
23
15
15
8
1
1
1
Host
Rabbit
251
110
17
1
Clonality
Polyclonal
Conjugate
This Survivin antibody is conjugated to HRP
16
14
11
11
8
8
8
6
6
6
6
6
4
3
3
3
3
3
2
2
2
2
2
2
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunohistochemistry (IHC), Western Blotting (WB)
290
145
126
121
116
108
53
43
24
11
11
11
10
9
6
2
2
2
2
1
1
Supplier
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Immunogen Full length recombinant human Survivin [UniProt# O15392]
Purification Immunogen affinity purified
Alternative Name Survivin (BIRC5 Antibody Abstract)
Background Gene Symbol: BIRC5
Molecular Weight Theoretical MW: 16.5 kDa
UniProt O15392
Research Area Neurology, Apoptosis/Necrosis, Glia marker, Cancer
Application Notes Western Blot 1 μg/mL, Immunohistochemistry 0.5 μg/mL, Immunocytochemistry/Immunofluorescence 1:50-1:250, Immunoprecipitation 1:10-1:500, Immunohistochemistry-Paraffin 0.5 μg/mL
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer PBS
Buffer contains: No Preservative
Preservative Without preservative
Storage 4 °C
Storage Comment Store at 4°C in the dark.
Supplier Images
Immunofluorescence (IF) image for anti-Survivin antibody (BIRC5)  (HRP) (ABIN268915) Immunocytochemistry/Immunofluorescence: Survivin Antibody [HRP] [ABIN268915H] - Telop...
Product cited in: Sun, Kawahara, Ehata, Nagamune: "AAG8 promotes carcinogenesis by activating STAT3." in: Cellular signalling, Vol. 26, Issue 9, pp. 1863-9, 2014 (PubMed). (Sample species: Human). Further details: Western Blotting

Wei, Chua, Grepper, So: "Soluble Frizzled-7 receptor inhibits Wnt signaling and sensitizes hepatocellular carcinoma cells towards doxorubicin." in: Molecular cancer, Vol. 10, pp. 16, 2011 (PubMed).

Wei, Chua, Grepper, So: "Blockade of Wnt-1 signaling leads to anti-tumor effects in hepatocellular carcinoma cells." in: Molecular cancer, Vol. 8, pp. 76, 2009 (PubMed).

Hauf, Cole, LaTerra, Zimmer, Schnapp, Walter, Heckel, van Meel, Rieder, Peters: "The small molecule Hesperadin reveals a role for Aurora B in correcting kinetochore-microtubule attachment and in maintaining the spindle assembly checkpoint." in: The Journal of cell biology, Vol. 161, Issue 2, pp. 281-94, 2003 (PubMed).

Kennedy, ODriscoll, Purcell, Fitz-Simons, McDermott, Hill, OHiggins, Parkinson, Linehan, Clynes: "Prognostic importance of survivin in breast cancer." in: British journal of cancer, Vol. 88, Issue 7, pp. 1077-83, 2003 (PubMed).

Grabowski, Kühnel, Mühr-Wilkenshoff, Heine, Stein, Höpfner, Germer, Scherübl: "Prognostic value of nuclear survivin expression in oesophageal squamous cell carcinoma." in: British journal of cancer, Vol. 88, Issue 1, pp. 115-9, 2003 (PubMed).

Miranda, Dyer, Grandis, Johnson: "Differential activation of apoptosis regulatory pathways during monocytic vs granulocytic differentiation: a requirement for Bcl-X(L)and XIAP in the prolonged survival of monocytic cells." in: Leukemia, Vol. 17, Issue 2, pp. 390-400, 2003 (PubMed).

Blanc-Brude, Yu, Simosa, Conte, Sessa, Altieri: "Inhibitor of apoptosis protein survivin regulates vascular injury." in: Nature medicine, Vol. 8, Issue 9, pp. 987-94, 2002 (PubMed).

Zhang, Hazarika, Ni, Weidner, Duvic: "Induction of apoptosis by bexarotene in cutaneous T-cell lymphoma cells: relevance to mechanism of therapeutic action." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 5, pp. 1234-40, 2002 (PubMed).

Giodini, Kallio, Wall, Gorbsky, Tognin, Marchisio, Symons, Altieri: "Regulation of microtubule stability and mitotic progression by survivin." in: Cancer research, Vol. 62, Issue 9, pp. 2462-7, 2002 (PubMed).

Yu, Leung, Ebert, Ng, Go, Wang, Chung, Malfertheiner, Sung: "Increased expression of survivin in gastric cancer patients and in first degree relatives." in: British journal of cancer, Vol. 87, Issue 1, pp. 91-7, 2002 (PubMed).

Mahotka, Liebmann, Wenzel, Suschek, Schmitt, Gabbert, Gerharz: "Differential subcellular localization of functionally divergent survivin splice variants." in: Cell death and differentiation, Vol. 9, Issue 12, pp. 1334-42, 2002 (PubMed).

Zhu, Fukuda, Cordis, Das, Maulik: "Anti-apoptotic protein survivin plays a significant role in tubular morphogenesis of human coronary arteriolar endothelial cells by hypoxic preconditioning." in: FEBS letters, Vol. 508, Issue 3, pp. 369-74, 2001 (PubMed).

Zeitlin, Shelby, Sullivan: "CENP-A is phosphorylated by Aurora B kinase and plays an unexpected role in completion of cytokinesis." in: The Journal of cell biology, Vol. 155, Issue 7, pp. 1147-57, 2001 (PubMed).

Background publications Chakravarti, Noll, Black, Finkelstein, Finkelstein, Dyson, Loeffler: "Quantitatively determined survivin expression levels are of prognostic value in human gliomas." in: Journal of clinical oncology : official journal of the American Society of Clinical Oncology, Vol. 20, Issue 4, pp. 1063-8, 2002 (PubMed).

Fortugno, Wall, Giodini, OConnor, Plescia, Padgett, Tognin, Marchisio, Altieri: "Survivin exists in immunochemically distinct subcellular pools and is involved in spindle microtubule function." in: Journal of cell science, Vol. 115, Issue Pt 3, pp. 575-85, 2002 (PubMed).

Wheatley, Carvalho, Vagnarelli, Earnshaw: "INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis." in: Current biology : CB, Vol. 11, Issue 11, pp. 886-90, 2001 (PubMed).