HLA Class I Histocompatibility Antigen, alpha Chain E (HLAE) antibody

Details for Product No. ABIN268938
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Antigen
Synonyms EA1.2, EA2.1, HLA-6.2, MHC, QA1
Reactivity
Human
(81), (4), (2), (2), (1), (1), (1)
Host
Mouse
(57), (23)
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
(4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
(41), (39), (32), (26), (10), (7), (4), (4), (2), (1), (1), (1), (1)
Pubmed 2 references available
Catalog no. ABIN268938
Quantity 0.1 mg
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Immunogen Recombinant human HLA-E denatured heavy chain.
Clone MEM-E-02
Isotype IgG1
Specificity This antibody reacts with the denaturated heavy chain of human HLA-E. Species Reactivity: Cross-reacts with Human. Not yet tested in other species. Localization: Type I membrane protein.
Alternative Name HLA class I alpha E / HLA-E
Background HLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is aheterodimer consisting of a heavy chain and a light chain (beta-2 microglobulin). Theheavy chain is anchored in the membrane. HLA E binds a restricted subset of peptidesderived from the leader peptides of other class I molecules. Alternate Names: anti-HLA class I histocompatibility antigen E alpha chain precursor antibody,anti-HLA-6.2 antibody, anti-Major histocompatibility complex class I E antibody.
Gene ID 3133
Application Notes Predicted molecular weight: 43 kDa. Optimal dilutions/concentrations should be determinedby the end user.
Restrictions For Research Use only
Buffer PBS with 15mM Sodium Azide. pH 7.4
Preservative Sodium azide
Storage 4 °C
General Menier, Saez, Horejsi et al.: "Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules." in: Human immunology, Vol. 64, Issue 3, pp. 315-26, 2003 (PubMed).

Mavilio, Lombardo, Kinter et al.: "Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection." in: The Journal of experimental medicine, Vol. 203, Issue 10, pp. 2339-50, 2006 (PubMed).

Hosts (57), (23)
Reactivities (81), (4), (2), (2), (1), (1), (1)
Applications (41), (39), (32), (26), (10), (7), (4), (4), (2), (1), (1), (1), (1)
Conjugates (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (4), (3), (2), (2), (1), (1), (1), (1), (1)
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