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MHC, Class I (Heavy Chain) antibody

Details for Product No. ABIN268938, Supplier: Log in to see
Antigen
  • H-2K
  • H-2K(d)
  • H2-K
  • K-f
  • Y-FA
  • YFV
Epitope
Heavy Chain
48
33
15
Reactivity
Human, Primate
159
137
67
30
23
19
17
17
17
17
8
3
3
1
1
Host
Mouse
278
34
30
Clonality (Clone)
Monoclonal ()
Conjugate
Un-conjugated
40
38
24
14
14
12
10
10
10
10
10
10
10
10
9
7
6
6
4
2
2
2
2
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), Western Blotting (WB)
280
79
70
57
57
49
33
24
11
5
4
3
2
2
2
2
2
1
1
Supplier
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Immunogen Recombinant human HLA-E denatured heavy chain.
Clone MEM-E-02
Isotype IgG1
Specificity The antibody MEM-E/02 specifically reacts with denaturated heavy chain of human HLA-E. HLA-E belongs to the MHC Class I molecules (MHC Class Ib, nonclassical) and it is expressed on the surface of all human cell types.
Purification Protein A purified
Alternative Name MHC Class I
Background Gene Symbol: HLA-E
Research Area Immunology, Major Histocompatibility Complex (MHC)
Application Notes Western Blot 1:1000, Immunohistochemistry, Immunohistochemistry-Paraffin 5-10 μg/mL
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer Phosphate Buffered Saline (PBS), approx. pH 7.4
Buffer contains: 15 mM Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment Store at 4°C. Do not freeze.
Product cited in: Ye, Li, Luo, Huang, Chen, Zhang, Cui, Zeng, Li: "Tumor-derived exosomes promote tumor progression and T-cell dysfunction through the regulation of enriched exosomal microRNAs in human nasopharyngeal carcinoma." in: Oncotarget, Vol. 5, Issue 14, pp. 5439-52, 2014 (PubMed). (Sample species: Human). Further details: Western Blotting

Mavilio, Lombardo, Kinter, Fogli, La Sala, Ortolano, Farschi, Follmann, Gregg, Kovacs, Marcenaro, Pende, Moretta, Fauci: "Characterization of the defective interaction between a subset of natural killer cells and dendritic cells in HIV-1 infection." in: The Journal of experimental medicine, Vol. 203, Issue 10, pp. 2339-50, 2006 (PubMed).

Menier, Saez, Horejsi, Martinozzi, Krawice-Radanne, Bruel, Le Danff, Reboul, Hilgert, Rabreau, Larrad, Pla, Carosella, Rouas-Freiss: "Characterization of monoclonal antibodies recognizing HLA-G or HLA-E: new tools to analyze the expression of nonclassical HLA class I molecules." in: Human immunology, Vol. 64, Issue 3, pp. 315-26, 2003 (PubMed).