IL-4 antibody (Biotin)

Catalog No. ABIN2689769

Product Details anti-IL-4 Antibody (Biotin)

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-4 antibody is conjugated to Biotin

Application: ELISA

Brand: BD Pharmingen™

Characteristics: The BVD6-24G2 antibody reacts with mouse interleukin-4 (IL-4). The immunogen used to generate the BVD6-24G2 hybridoma was recombinant IL-4. This is a non-neutralizing antibody. This antibody is routinely tested by ELISA Detection. Other applications were tested during antibody development only or reported in the literature.

BD Pharmingen™ Biotin Rat Anti-Mouse IL-4 - Biotin - Clone BVD6-24G2 - Isotype Rat IgG1 - Reactivity Ms - 0.5 mg

Purification: The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.

Immunogen: Recombinant IL-4

Clone: BVD6

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Concentration: 0.5 mg/mL

Buffer: Aqueous buffered solution containing ≤0.09 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: The antibody was conjugated with biotin under optimum conditions, and unreacted biotin was removed.

Storage: 4 °C

Storage Comment: Store undiluted at 4°C and protected from prolonged exposure to light. Do not freeze.

References for anti-IL-4 antibody (Biotin) (ABIN2689769)

Shirai, Sierra, Kelly, Klinman: "Individual cells simultaneously produce both IL-4 and IL-6 in vivo." in: Cytokine, Vol. 6, Issue 3, pp. 329-36, (1994) (PubMed).

Bogen, Fogelman, Abbas: "Analysis of IL-2, IL-4, and IFN-gamma-producing cells in situ during immune responses to protein antigens." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 150, Issue 10, pp. 4197-205, (1993) (PubMed).

Abrams, Roncarolo, Yssel, Andersson, Gleich, Silver: "Strategies of anti-cytokine monoclonal antibody development: immunoassay of IL-10 and IL-5 in clinical samples." in: Immunological reviews, Vol. 127, Issue 9-10, pp. 5-24, (1992) (PubMed).

Chatelain, Varkila, Coffman: "IL-4 induces a Th2 response in Leishmania major-infected mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 148, Issue 4, pp. 1182-7, (1992) (PubMed).

Target Details for IL-4

Target: IL-4 (IL4) (Interleukin 4 (IL4))

Alternative Name: IL-4 (IL4 Products)

Synonyms: IL4 antibody, IL-4 antibody, BCGF-1 antibody, BCGF1 antibody, BSF-1 antibody, BSF1 antibody, Il-4 antibody, Il4e12 antibody, IL2 antibody, interleukin 4 antibody, IL4 antibody, Il4 antibody

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Proton Transport, Activated T Cell Proliferation