IRF2 antibody (AA 81-180)

Catalog No. ABIN2690174

Product Details anti-IRF2 Antibody

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Binding Specificity: AA 81-180

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IRF2 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Human, Mouse, Rat

Predicted Reactivity: Cow,Sheep,Pig,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human IRF2

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for IRF2

Target: IRF2 (Interferon Regulatory Factor 2 (IRF2))

Alternative Name: IRF2 (IRF2 Products)

Synonyms: IRF-2 antibody, 9830146E22Rik antibody, AI646973 antibody, Irf-2 antibody, irf2b antibody, zgc:103451 antibody, irf-2 antibody, wu:fc74h04 antibody, zgc:76951 antibody, interferon regulatory factor 2 antibody, interferon regulatory factor 2 L homeolog antibody, interferon regulatory factor 2a antibody, IRF2 antibody, Irf2 antibody, irf2 antibody, irf2.L antibody, irf2a antibody

Background:

Synonyms: IRF-2, Interferon regulatory factor 2, IRF2

Background: Specifically binds to the upstream regulatory region of type I IFN and IFN-inducible MHC class I genes (the interferon consensus sequence (ICS)) and represses those genes. Also acts as an activator for several genes including H4 and IL7. Constitutively binds to the ISRE promoter to activate IL7. Involved in cell cycle regulation through binding the site II (HiNF-M) promoter region of H4 and activating transcription during cell growth. Antagonizes IRF1 transcriptional activation.

Gene ID: 3660

UniProt: P14316