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Discs, Large Homolog 1 (Drosophila) (DLG1) antibody

Details for Product No. ABIN269417, Supplier: Log in to see
Antigen
  • DLG1
  • Dlgh1
  • SAP97
  • B130052P05Rik
  • E-dlg/SAP97
  • SAP-97
  • mKIAA4187
  • DLGH1
  • dJ1061C18.1.1
  • hdlg
  • discs, large homolog 1 (Drosophila)
  • DLG1
  • Dlg1
Alternatives
anti-Rat (Rattus) Discs, Large Homolog 1 (Drosophila) antibody for Western Blotting
Reactivity
Human, Mouse (Murine), Rat (Rattus)
42
25
22
3
2
2
2
2
1
1
1
1
1
1
1
1
Host
Rabbit
18
17
16
1
Clonality
Polyclonal
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunoprecipitation (IP), Western Blotting (WB)
48
20
14
8
7
4
4
4
2
2
1
1
1
Options
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Available images

Immunogen Synthetic peptide corresponding to residues V(115) L P S E R I S P Q V P N E V L G P E(133) of rat SAP97.
Isotype IgG
Specificity Detects SAP 97 from rat tissues. No cross-reactivity to other proteins, including synapse-associated protein family members, has been observed.
Purification Ammonium sulfate precipitation
Alternative Name DLG1 (DLG1 Antibody Abstract)
Background Gene Symbol: DLG1
Gene ID 1739
Pathways Regulation of Actin Filament Polymerization, Cell-Cell Junction Organization, Production of Molecular Mediator of Immune Response
Application Notes Western Blot 1:500 - 1:5000, Immunohistochemistry 1:1000, Immunocytochemistry/Immunofluorescence 1:20 - 1:200, Immunoprecipitation 1:10 - 1:500, Immunohistochemistry-Frozen 1:1000WB: Detects an approx. 140 kDa protein representing SAP 97 from rat brain extract. IHC: Staining of SAP 97 in rat hippocampus results in intense neuronal cell body and dendrite staining.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer PBS and 1 mg/mL BSA
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage -20 °C
Storage Comment Store at -20°C. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-Discs, Large Homolog 1 (Drosophila) (DLG1) antibody (ABIN269417) Western Blot: DLG1 Antibody [ABIN269417] - Analysis of 25 ug of C6 (lane 1), PC12 (la...
Immunofluorescence (IF) image for anti-Discs, Large Homolog 1 (Drosophila) (DLG1) antibody (ABIN269417) Immunocytochemistry/Immunofluorescence: DLG1 Antibody [ABIN269417] - Analysis of SAP9...
Immunofluorescence (IF) image for anti-Discs, Large Homolog 1 (Drosophila) (DLG1) antibody (ABIN269417) Immunocytochemistry/Immunofluorescence: DLG1 Antibody [ABIN269417] - Analysis of SAP9...
Product cited in: Gardner, Naren, Bahouth et al.: "Assembly of an SAP97-AKAP79-cAMP-dependent protein kinase scaffold at the type 1 PSD-95/DLG/ZO1 motif of the human beta(1)-adrenergic receptor generates a receptosome involved in receptor recycling ..." in: The Journal of biological chemistry, Vol. 282, Issue 7, pp. 5085-99, 2007 (PubMed).

Background publications Gomperts: "Clustering membrane proteins: It's all coming together with the PSD-95/SAP90 protein family." in: Cell, Vol. 84, Issue 5, pp. 659-62, 1996 (PubMed).

Mueller, Kistner, Veh, Cases-Langhoff, Becker, Gundelfinger, Garner: "Molecular characterization and spatial distribution of SAP97, a novel presynaptic protein homologous to SAP90 and the Drosophila discs-large tumor suppressor protein." in: The Journal of neuroscience : the official journal of the Society for Neuroscience, Vol. 15, Issue 3 Pt 2, pp. 2354-66, 1995 (PubMed).

Cho, Hunt, Kennedy: "The rat brain postsynaptic density fraction contains a homolog of the Drosophila discs-large tumor suppressor protein." in: Neuron, Vol. 9, Issue 5, pp. 929-42, 1992 (PubMed).