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HDAC4 antibody (Histone Deacetylase 4) (C-Term)

Details for Product anti-HDAC4 Antibody No. ABIN269450, Supplier: Log in to see
Antigen
  • 4932408F19Rik
  • AHO3
  • AI047285
  • BDMR
  • CG1770
  • DanaGF18710
  • dana_GLEANR_19966
  • DHDAC4
  • dHDAC4
  • Dmel\\CG1770
  • dmHDA405
  • GC1770
  • GF18710
  • HA6116
  • HD4
  • HDAC
  • HDAC-4
  • HDAC-A
  • HDAC4
  • hdac4
  • HDAC4a
  • HDACA
  • wu:fa96d08
  • wu:fc56f08
  • zgc:152701
Epitope
C-Term
57
31
19
15
9
9
5
4
4
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human, Mouse (Murine), Rat (Rattus)
315
123
92
8
3
3
2
2
2
2
1
1
Host
Rabbit
225
96
2
Clonality
Polyclonal
Conjugate
This HDAC4 antibody is un-conjugated
12
11
11
7
4
4
4
4
3
3
3
3
3
3
3
3
3
2
2
2
1
1
1
1
1
1
1
Application
Immunocytochemistry (ICC), Immunofluorescence (IF), Immunoprecipitation (IP), Microarray (MA), Western Blotting (WB)
293
130
56
42
42
33
30
25
12
11
5
1
1
1
1
1
Supplier
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Immunogen Synthetic peptide: DQPVELLNPARVNHM with C-terminal added lysine, conjugated to KLH, corresponding to amino acids 14-28 of Human HDAC4.
Isotype IgG
Specificity HDAC4
Cross-Reactivity (Details) Expected to cross-react with Chicken (93% identity with immunogen) due to sequence homology. Not yet tested in other species.
Purification Immunogen affinity purified
Alternative Name Histone Deacetylase 4/HDAC4 (HDAC4 Antibody Abstract)
Background Gene Symbol: HDAC4
Molecular Weight Theoretical MW: 140 kDa
Gene ID 9759, 208727, 363287
UniProt P56524
Application Notes Western Blot 1:500-1:1000, Immunocytochemistry/Immunofluorescence 1:250, Immunoprecipitation 10-20 μg, Microarray
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 1.0 mg/mL
Buffer 0.01 M phosphate buffered saline, pH 7.4, containing 1 % bovine serum albumin
Buffer contains: 15 mM Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Supplier Images
Immunoprecipitation (IP) image for anti-HDAC4 antibody (Histone Deacetylase 4) (C-Term) (ABIN269450) Immunoprecipitation: Histone Deacetylase 4/HDAC4 Antibody [ABIN269450] - Rabbit Anti-...
Product cited in: Geng, Cuneo, Fu, Tu, Atadja, Hallahan: "Histone deacetylase (HDAC) inhibitor LBH589 increases duration of gamma-H2AX foci and confines HDAC4 to the cytoplasm in irradiated non-small cell lung cancer." in: Cancer research, Vol. 66, Issue 23, pp. 11298-304, 2006 (PubMed).

Background publications Khochbin, Verdel, Lemercier, Seigneurin-Berny: "Functional significance of histone deacetylase diversity." in: Current opinion in genetics & development, Vol. 11, Issue 2, pp. 162-6, 2001 (PubMed).

Fischle, Kiermer, Dequiedt, Verdin: "The emerging role of class II histone deacetylases." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 79, Issue 3, pp. 337-48, 2001 (PubMed).

Grozinger, Hassig, Schreiber: "Three proteins define a class of human histone deacetylases related to yeast Hda1p." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 96, Issue 9, pp. 4868-73, 1999 (PubMed).

Wang, Bertos, Vezmar, Pelletier, Crosato, Heng, Thng, Han, Yang: "HDAC4, a human histone deacetylase related to yeast HDA1, is a transcriptional corepressor." in: Molecular and cellular biology, Vol. 19, Issue 11, pp. 7816-27, 1999 (PubMed).