You are viewing an incomplete version of our website. Please click to reload the website as full version.

SOCS2 antibody (Suppressor of Cytokine Signaling 2)

Details for Product anti-SOCS2 Antibody No. ABIN269520, Supplier: Log in to see
Antigen
  • si:dkey-202b22.1
  • socs2
  • cis2
  • ssi2
  • cish2
  • ssi-2
  • socs-2
  • stati2
  • CIS2
  • Cish2
  • SOCS-2
  • SSI-2
  • SSI2
  • STATI2
  • 8030460M17
  • AI527257
  • AW108012
  • D130043N08Rik
  • JAB
  • hg
  • Socs-2
  • suppressor of cytokine signaling 2
  • SOCS2
  • socs2
  • LOC100229201
  • Socs2
Alternatives
anti-Human SOCS2 antibody for ELISA
Reactivity
Human, Mouse (Murine), Rat (Rattus)
50
19
16
3
3
2
2
Host
Rabbit
46
5
2
Clonality
Polyclonal
Conjugate
This SOCS2 antibody is un-conjugated
1
1
Application
ELISA, Western Blotting (WB)
36
14
10
9
8
1
1
1
1
Options
Supplier
Log in to see
Supplier Product No.
Log in to see
Request

Get this product for free

It's quick and easy to submit your validation proposal. I want to validate this product

Learn more

Available images

Immunogen Synthetic peptide (PTRLKDYLEEYKFQV) correspondingto amino acids 184-198 of human, rat and mouse SOCS 2 (NP_003868).
Specificity SOCS2
Cross-Reactivity (Details) Not yet tested in other species.
Purification Immunogen affinity purified
Alternative Name SOCS-2 (SOCS2 Antibody Abstract)
Background Gene Symbol: SOCS2
Molecular Weight Theoretical MW: 22 kDa
Gene ID 8835
UniProt O14508
Research Area Signaling, Cytokines
Pathways JAK-STAT Signaling
Application Notes Western Blot 1:500-1:1000, ELISA 1:5000-1:20000The observed molecular weight of the protein may vary from the listed predicted molecular weight due to post translational modifications, post translation cleavages, relative charges, and other experimental factors.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Concentration 0.2 mg/mL
Buffer PBS
Buffer contains: 0.05 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Do not freeze.
Storage 4 °C
Storage Comment Store at 4°C. Do not freeze.
Supplier Images
Western Blotting (WB) image for anti-SOCS2 antibody (Suppressor of Cytokine Signaling 2) (ABIN269520) Western Blot: SOCS2 Antibody [ABIN269520] - Western blot analysis of the Hela cell ly...
Product cited in: Inagaki, Lin, Goetz, Mohammadi, Mangelsdorf, Kliewer: "Inhibition of growth hormone signaling by the fasting-induced hormone FGF21." in: Cell metabolism, Vol. 8, Issue 1, pp. 77-83, 2008 (PubMed).

Ransome, Turnley: "Analysis of neuronal subpopulations in mice over-expressing suppressor of cytokine signaling-2." in: Neuroscience, Vol. 132, Issue 3, pp. 673-87, 2005 (PubMed).

Gregorieff, Pyronnet, Sonenberg, Veillette: "Regulation of SOCS-1 expression by translational repression." in: The Journal of biological chemistry, Vol. 275, Issue 28, pp. 21596-604, 2000 (PubMed).

Ram, Waxman: "SOCS/CIS protein inhibition of growth hormone-stimulated STAT5 signaling by multiple mechanisms." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35553-61, 2000 (PubMed).

Background publications Krebs, Hilton: "SOCS proteins: negative regulators of cytokine signaling." in: Stem cells (Dayton, Ohio), Vol. 19, Issue 5, pp. 378-87, 2001 (PubMed).

Krebs, Hilton: "SOCS: physiological suppressors of cytokine signaling." in: Journal of cell science, Vol. 113 ( Pt 16), pp. 2813-9, 2000 (PubMed).

Yoshimura: "The CIS family: negative regulators of JAK-STAT signaling." in: Cytokine & growth factor reviews, Vol. 9, Issue 3-4, pp. 197-204, 1999 (PubMed).

Hilton, Richardson, Alexander, Viney, Willson, Sprigg, Starr, Nicholson, Metcalf, Nicola: "Twenty proteins containing a C-terminal SOCS box form five structural classes." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 95, Issue 1, pp. 114-9, 1998 (PubMed).