CDKN1B antibody (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1))

Details for Product anti-CDKN1B Antibody No. ABIN269609, Supplier: Log in to see
Antigen
  • CDKN1B
  • CIB
  • CIBP
  • KIP1
  • PRKDCIP
  • SIP2-28
  • p27Kip1
  • AA408329
  • AI843786
  • Kip1
  • p27
  • CDKN4
  • Cdki1b
  • P27KIP1
  • MEN1B
  • MEN4
  • cdkn1bl
  • cdkn1b
  • sb:cb611
  • wu:fb63g10
  • wu:fb64g10
  • wu:fe18e03
  • FAM14D
  • ISG12
  • ISG12A
  • P27
  • 1500011J20Rik
  • 2610202L11Rik
  • Bridge-1
  • cyclin-dependent kinase inhibitor 1B (p27, Kip1)
  • calcium and integrin binding 1 (calmyrin)
  • cyclin kinase inhibitor p30 Kip1
  • cyclin-dependent kinase inhibitor 1B
  • cyclin-dependent kinase inhibitor 1Ba
  • cyclin-dependent kinase inhibitor 1Bb
  • interferon, alpha-inducible protein 27
  • proteasome (prosome, macropain) 26S subunit, non-ATPase, 9
  • CDKN1B
  • CIB1
  • LOC100689401
  • Cdkn1b
  • cdkn1ba
  • cdkn1bb
  • IFI27
  • Psmd9
Alternatives
anti-Human CDKN1B antibody for BioImaging
Reactivity
Human
708
362
299
93
44
27
18
12
8
7
3
3
2
2
1
1
1
Host
Rabbit
480
228
36
3
2
1
Clonality
Polyclonal
Conjugate
This CDKN1B antibody is un-conjugated
37
34
32
31
25
25
9
9
7
7
5
5
5
5
5
5
5
5
5
4
4
3
3
2
2
2
2
2
2
2
1
Application
Immunoprecipitation (IP), ELISA, Western Blotting (WB)
542
327
207
171
164
104
104
102
53
37
28
14
10
3
3
1
1
1
Options
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Immunogen Full length protein (Human).
Specificity No reaction is observed against other related tumor supressor proteins.
Purification Delipidation and Defibrination
Alternative Name p27/Kip1 (CDKN1B Antibody Abstract)
Background Gene Symbol: CDKN1B
Gene ID 1027
Pathways Cell Division Cycle, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Sensory Perception of Sound, Mitotic G1-G1/S Phases, DNA Replication, Positive Regulation of Endopeptidase Activity, Synthesis of DNA, Autophagy
Application Notes Western Blot 1:1000-1:4000, ELISA 1:10000-1:40000, Immunoprecipitation 1:100This antibody is suitable for use in ELISA, immunoprecipitation, co-immunoprecipitation and western blotting. Expect a band at ~27 kDa in size corresponding - p27 by western blotting in the appropriate cell lysate or extract. Anti-p27 is suitable for the detection by immunoblot of human p27. No reactivity is observed with p27 from mouse. This antibody is suitable for immmunoprecipitation of in vitro translated protein and cell lysates and will co-precipitate associated proteins.
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer 0.02 M Potassium Phosphate, 0.15 M Sodium Chloride, pH 7.2
Buffer contains: 0.01 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-CDKN1B antibody (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1)) (ABIN269609) anti-Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1) (CDKN1B) antibody
Western Blotting (WB) image for anti-CDKN1B antibody (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1)) (ABIN269609) Western Blot: p27/Kip1 Antibody [ABIN269609] - Analysis of p27 protein in MCF7 whole ...
Western Blotting (WB) image for anti-CDKN1B antibody (Cyclin-Dependent Kinase Inhibitor 1B (p27, Kip1)) (ABIN269609) Western Blot: p27/Kip1 Antibody [ABIN269609] - Lane 1: HEK293 pcDNA3. Lane 2: HEK293 ...
Product cited in: Kushwaha, Raichlin, Sheinin, Kremers, Chandrasekaran, Brunn, Platt: "Sirolimus affects cardiomyocytes to reduce left ventricular mass in heart transplant recipients." in: European heart journal, Vol. 29, Issue 22, pp. 2742-50, 2008 (PubMed).

Background publications Polyak, Lee, Erdjument-Bromage, Koff, Roberts, Tempst, Massagué: "Cloning of p27Kip1, a cyclin-dependent kinase inhibitor and a potential mediator of extracellular antimitogenic signals." in: Cell, Vol. 78, Issue 1, pp. 59-66, 1994 (PubMed).

Toyoshima, Hunter: "p27, a novel inhibitor of G1 cyclin-Cdk protein kinase activity, is related to p21." in: Cell, Vol. 78, Issue 1, pp. 67-74, 1994 (PubMed).