WNK Lysine Deficient Protein Kinase 4 (WNK4) antibody

Details for Product No. ABIN269722
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Antigen
Synonyms 2010002J11Rik, Pha2b, Prkwnk4, Ac2-059, PHA2B, PRKWNK4, WNK4
Reactivity
Human, Mouse (Murine), Rat (Rattus)
(22), (19), (18)
Host
Rabbit
(24), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(15), (10), (7), (4), (1)
Pubmed 3 references available
Catalog no. ABIN269722
Quantity 25 µL
Price
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Immunogen A synthetic peptide sequence made to a region of thehuman protein between residues 200-300.
Specificity ABIN153223 is specific for WNK4 protein. Species Reactivity: ABIN153223 can be used to detect mouse and human (very weakly) WNK4 protein. Localization: Cell junctions, tight junctions.
Alternative Name WNK4
Background WNK kinases play an important role in hypertension. WNK4 localizes to both tightjunctions and to a segment of kidney involved in salt, potassium, and pH homeostasis,the distal nephron. Alternate Names: Anti-PHA 2B antibody, Anti-PHA2B antibody, Anti-PRKWNK 4 antibody, Anti-PRKWNK4antibody, Anti-Protein kinase lysine deficient 4 antibody, Anti-Protein kinase with nolysine 4 antibody, Anti-Serine/threonine protein kinase WNK4 antibody, Anti-WNK lysinedeficient protein kinase 4 antibody.
Gene ID 65266
Research Area Signaling
Application Notes Suggested working dilutions: Western Blot 2 ug/ml. Positive Controls: Mouse kidney lysate
Restrictions For Research Use only
Format Liquid
Concentration 0.92 mg/ml
Storage -20 °C
General Wilson, Disse-Nicodème, Choate et al.: "Human hypertension caused by mutations in WNK kinases." in: Science (New York, N.Y.), Vol. 293, Issue 5532, pp. 1107-12, 2001 (PubMed).

Kahle, Gimenez, Hassan et al.: "WNK4 regulates apical and basolateral Cl- flux in extrarenal epithelia." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 101, Issue 7, pp. 2064-9, 2004 (PubMed).

Song, Hu, Riazi et al.: "Regulation of blood pressure, the epithelial sodium channel (ENaC), and other key renal sodium transporters by chronic insulin infusion in rats." in: American journal of physiology. Renal physiology, Vol. 290, Issue 5, pp. F1055-64, 2006 (PubMed).

Hosts (24), (1)
Reactivities (22), (19), (18)
Applications (15), (10), (7), (4), (1)
Conjugates (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (6), (1), (1), (1)
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