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NOTCH2 antibody (Notch 2) (AA 2396-2409)

Details for Product anti-NOTCH2 Antibody No. ABIN269894, Supplier: Log in to see
Antigen
  • AGS2
  • AI853703
  • HJCYS
  • hN2
  • N2
  • notch6
  • sb:cb884
Alternatives
anti-Human NOTCH2 antibody for ELISA
Epitope
AA 2396-2409
20
17
15
11
9
9
6
5
4
4
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
1
1
1
1
Reactivity
Human
152
76
54
9
4
3
3
3
1
1
1
1
1
1
Host
Rabbit
120
20
18
17
13
2
Clonality
Polyclonal
Conjugate
This NOTCH2 antibody is un-conjugated
10
6
5
4
3
3
3
2
2
2
2
2
2
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (IHC), ELISA, Western Blotting (WB)
88
87
47
39
27
13
12
6
6
2
2
2
2
1
1
1
Supplier
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Immunogen Synthetic Peptide: C-NAAERTPSHSGHLQaa 2396-2409 (the total protein is 2471 aa).
Isotype IgG
Cross-Reactivity (Details) Expected to cross-react with Human. The peptide sequence shows 100% alignment with human, dog,chimpanzee sequence. Only one (1) amino acid difference is found in mouse,this change is non-conservative. Based on the sequence we expect this antibody to react as well with rat,mouse.
Purification Unpurified
Alternative Name Notch-2 (NOTCH2 Antibody Abstract)
Background Gene Symbol: NOTCH2
Pathways Notch Signaling
Application Notes Western Blot 1:400-1:2000, ELISA 1:30000-1:90000, Immunohistochemistry 1:200-1:800, Immunohistochemistry-Paraffin 1:500
Comment

The antibodies are intended for use in vitro experiments only. Our antibodies have not been tested nor are recommended for use in vivo.

Restrictions For Research Use only
Format Liquid
Buffer 0.02 M Potassium Phosphate with 0.15 M Sodium Chloride pH 7.2 (Concentration 75 mg/mL by Refractometry)
Buffer contains: 0.01 % Sodium Azide
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C,-20 °C
Storage Comment Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Supplier Images
Western Blotting (WB) image for anti-NOTCH2 antibody (Notch 2) (AA 2396-2409) (ABIN269894) anti-Notch 2 (NOTCH2) (AA 2396-2409) antibody
Western Blotting (WB) image for anti-NOTCH2 antibody (Notch 2) (AA 2396-2409) (ABIN269894) Western Blot: Notch-2 Antibody [ABIN269894] - Analysis of a band at 110 kDa correspon...
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) image for anti-NOTCH2 antibody (Notch 2) (AA 2396-2409) (ABIN269894) Immunohistochemistry-Paraffin: Notch-2 Antibody [ABIN269894] - Diluted 1:500 to detec...
Product cited in: Yu, Qi, Feng, Zhang, Zhang, Tian: "Interference of Notch 2 inhibits the progression of gliomas and induces cell apoptosis by induction of the cell cycle at the G0/G1 phase." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 734-8, 2014 (PubMed). Further details: Immunohistochemistry

Gupta, Li, Abedin, Wang, Schneider, Najafian, Rosenberg: "Effect of Notch activation on the regenerative response to acute renal failure." in: American journal of physiology. Renal physiology, Vol. 298, Issue 1, pp. F209-15, 2009 (PubMed).

Chen, Oh, Hinman, Abraham: "Visualization of APP dimerization and APP-Notch2 heterodimerization in living cells using bimolecular fluorescence complementation." in: Journal of neurochemistry, Vol. 97, Issue 1, pp. 30-43, 2006 (PubMed).

Rutenberg, Fischer, Jia, Gessler, Zhong, Mercola: "Developmental patterning of the cardiac atrioventricular canal by Notch and Hairy-related transcription factors." in: Development (Cambridge, England), Vol. 133, Issue 21, pp. 4381-90, 2006 (PubMed).