CD8 antibody (FITC)

Catalog No. ABIN2704340

Product Details anti-CD8 Antibody (FITC)

Target: CD8

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD8 antibody is conjugated to FITC

Application: Flow Cytometry (FACS)

Characteristics: Clone OKT8, a mouse monoclonal antibody, binds with a 32-34 kDa type I transmembrane glycoprotein known as CD8 a member of the immunoglobulin superfamily. OKT8 binds to CD8α, which forms either a homodimer or a heterodimer with CD8β. It is expressed on the surface of cytotoxic T cells, NK cells, cortical thymocytes, and on some dendritic cells. CD8 functions as a co-receptor for T-cell receptors and specifically binds to class I MHC for antigen recognition and T-cell activation.

Purification: Purified

Purity: >95 %

Grade: GMP Grade

Immunogen: Human peripheral blood T lymphocytes

Clone: OKT8

Isotype: IgG2a kappa

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100 μg/mL

Buffer: PBS pH 7.2, 0.2 % (w/v) BSA, 0.09 % (w/v) sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for CD8

Target: CD8

Alternative Name: CD8 (CD8 Products)

Synonyms: CD8 antibody, Leu2 antibody, MAL antibody, p32 antibody, CD8a molecule antibody, CD8A antibody

Background: Clone OKT8, a mouse monoclonal antibody, binds with a 32-34 kDa type I transmembrane glycoprotein known as CD8 a member of the immunoglobulin superfamily. OKT8 binds to CD8α, which forms either a homodimer or a heterodimer with CD8β. It is expressed on the surface of cytotoxic T cells, NK cells, cortical thymocytes, and on some dendritic cells. CD8 functions as a co-receptor for T-cell receptors and specifically binds to class I MHC for antigen recognition and T-cell activation.

NCBI Accession: NM_001768

UniProt: P01732