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Poly (ADP-Ribose) Polymerase 1 (PARP1) (N-Term), (Cleavage Site) antibody

Details for Product No. ABIN271522
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Antigen
Synonyms
5830444G22Rik, AI893648, ARTD1, Adprp, Adprt1, C80510, PARP, PPOL, parp-1, sPARP-1, ADPRT, ADPRT 1, ADPRT1, PARP-1, pADPRT-1, Adprt, Parp-1, BEST:LD21673, CG17685, CG17696, CG17718, CG40411, D.PARP, D ... show more
5830444G22Rik, AI893648, ARTD1, Adprp, Adprt1, C80510, PARP, PPOL, parp-1, sPARP-1, ADPRT, ADPRT 1, ADPRT1, PARP-1, pADPRT-1, Adprt, Parp-1, BEST:LD21673, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, LD21673.3prime, PARP1, dPARP, parp, adprt1, padprt-1, ppol, ART7.1, ART1 show less
Epitope
N-Term, Cleavage Site
(35), (9), (9), (9), (9), (9), (9), (9), (9), (9), (9), (8), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(208), (44), (41), (23), (13), (2), (2), (2), (2), (1), (1), (1)
Host
Rabbit
(216), (28), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(13), (13), (12), (12), (12), (11), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
(141), (115), (85), (46), (29), (23), (18), (17), (10), (9), (9), (1), (1), (1), (1), (1)
Pubmed 4 references available
Quantity 0.1 mL
Shipping to United States (Change)
Catalog No. ABIN271522
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  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen Synthetic peptide (Human) corresponding to N-terminus of cleavage site (214/215) of human PARP
Isotype IgG
Specificity This specifically recognizes the 85 kDa fragment of cleaved PARP and can be used as marker for detecting apoptotic cells.
Cross-Reactivity (Details) Not yet tested in other species.
Purification affinity purified
Alternative Name PARP1
Background Alternate Names: anti-ADP ribosyltransferase NAD+ antibody, anti-pADPRT1 antibody, anti-PARP1antibody, anti-Poly adenosine diphosphate ADP ribose polymerase antibody, anti-PolyADP ribose polymerase 1 antibody, anti-Poly ADP ribose synthetase 1 antibody,anti-PPOL antibody.
Gene Symbol: PARP1
Gene ID 142
Application Notes Immunocytochemistry: Use at a dilution of 1/100. Western Blot: Use at a dilution of 1/1000. Predicted molecular weight: 85 kDa. Can be blocked with PARP Cleavage site antibody peptide. Optimal dilutions/concentrations should be determined by the end user.
Recommended dilutions: Immunocytochemistry/Immunofluorescence 1:10-1:2000, Western Blot 1:100-1:2000, Immunohistochemistry
Restrictions For Research Use only
Format Liquid
Buffer PBS containing, 1mg/ml BSA and 50 % Glycerol (IgG, protease free), Sodium Azide
Preservative Sodium azide
Precaution of Use WARNING: Reagents contain sodium azide. Sodium azide is very toxic if ingested or inhaled. Avoid contact with skin, eyes, or clothing. Wear eye or face protection when handling. If skin or eye contact occurs, wash with copious amounts of water. If ingested or inhaled, contact a physician immediately. Sodium azide yields toxic hydrazoic acid under acidic conditions. Dilute azide-containing compounds in running water before discarding to avoid accumulation of potentially explosive deposits in lead or copper plumbing.
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
General Duriez, Shah: "Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 75, Issue 4, pp. 337-49, 1998 (PubMed).

Germain, Affar, DAmours et al.: "Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7." in: The Journal of biological chemistry, Vol. 274, Issue 40, pp. 28379-84, 1999 (PubMed).

Leemans, Juffermans, Florquin et al.: "Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 7, pp. 4604-11, 2001 (PubMed).

Turturro, Arnold, Frist et al.: "Model of inhibition of the NPM-ALK kinase activity by herbimycin A." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 1, pp. 240-5, 2002 (PubMed).

Hosts (216), (28), (1)
Reactivities (208), (44), (41), (23), (13), (2), (2), (2), (2), (1), (1), (1)
Applications (141), (115), (85), (46), (29), (23), (18), (17), (10), (9), (9), (1), (1), (1), (1), (1)
Conjugates (13), (13), (12), (12), (12), (11), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (35), (9), (9), (9), (9), (9), (9), (9), (9), (9), (9), (8), (7), (6), (6), (6), (6), (6), (6), (6), (6), (6), (6), (5), (4), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN271522
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
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