Poly (ADP-Ribose) Polymerase 1 (PARP1) antibody

Details for Product No. ABIN271522
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Antigen
Synonyms
5830444G22Rik, AI893648, ARTD1, Adprp, Adprt1, C80510, PARP, PPOL, parp-1, sPARP-1, ADPRT, ADPRT 1, ADPRT1, PARP-1, pADPRT-1, Adprt, Parp-1, BEST:LD21673, CG17685, CG17696, CG17718, CG40411, D.PARP, D ... show more
5830444G22Rik, AI893648, ARTD1, Adprp, Adprt1, C80510, PARP, PPOL, parp-1, sPARP-1, ADPRT, ADPRT 1, ADPRT1, PARP-1, pADPRT-1, Adprt, Parp-1, BEST:LD21673, CG17685, CG17696, CG17718, CG40411, D.PARP, Dm.pARTa, Dmel\\CG40411, LD21673.3prime, PARP1, dPARP, parp, adprt1, padprt-1, ppol, ART7.1, ART1 show less
Reactivity
Human
(142), (41), (38), (23), (13), (2), (2), (2), (2), (1), (1), (1)
Host
Rabbit
(144), (28), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunofluorescence (IF), Western Blotting (WB)
(124), (46), (44), (31), (29), (23), (17), (16), (10), (9), (7), (2), (1), (1), (1), (1)
Pubmed 4 references available
Catalog no. ABIN271522
Quantity 0.1 mL
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Immunogen Synthetic peptide (Human) corresponding to N-terminus of cleavage site (214/215) ofhuman PARP.
Isotype IgG
Specificity This antibody specifically recognizes the 85 kDa fragment of cleaved PARP and can beused as marker for detecting apoptotic cells. Species Reactivity: Cross-reacts with Cow and Human. Not yet tested in other species. Localization: Nuclear.
Cross-Reactivity Human
Purification Aff - Purified
Alternative Name PARP1
Background Alternate Names: anti-ADP ribosyltransferase NAD+ antibody, anti-pADPRT1 antibody, anti-PARP1antibody, anti-Poly adenosine diphosphate ADP ribose polymerase antibody, anti-PolyADP ribose polymerase 1 antibody, anti-Poly ADP ribose synthetase 1 antibody,anti-PPOL antibody.
Gene ID 142
Application Notes Positive Controls: HeLa cells treated with staurosporine at 0.5 uM for 5 hours or bovine PARP cleaved bycaspase 3.
Restrictions For Research Use only
Format Liquid
Buffer Preservative: 0.05% Sodium AzideConstituents: 50% Glycerol, PBS, 1mg/ml BSA (IgG,protease free). pH. Preservative: 0.05% Sodium AzideConstituents: 50% Glycerol, PBS, 1mg/ml BSA (IgG,protease free). pH.
Preservative Sodium azide
General Duriez, Shah: "Cleavage of poly(ADP-ribose) polymerase: a sensitive parameter to study cell death." in: Biochemistry and cell biology = Biochimie et biologie cellulaire, Vol. 75, Issue 4, pp. 337-49, 1998 (PubMed).

Germain, Affar, DAmours et al.: "Cleavage of automodified poly(ADP-ribose) polymerase during apoptosis. Evidence for involvement of caspase-7." in: The Journal of biological chemistry, Vol. 274, Issue 40, pp. 28379-84, 1999 (PubMed).

Leemans, Juffermans, Florquin et al.: "Depletion of alveolar macrophages exerts protective effects in pulmonary tuberculosis in mice." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 7, pp. 4604-11, 2001 (PubMed).

Turturro, Arnold, Frist et al.: "Model of inhibition of the NPM-ALK kinase activity by herbimycin A." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 8, Issue 1, pp. 240-5, 2002 (PubMed).

Hosts (144), (28), (1)
Reactivities (142), (41), (38), (23), (13), (2), (2), (2), (2), (1), (1), (1)
Applications (124), (46), (44), (31), (29), (23), (17), (16), (10), (9), (7), (2), (1), (1), (1), (1)
Conjugates (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (25), (9), (4), (3), (3), (3), (3), (3), (3), (3), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
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