Contactin 6 (CNTN6) antibody

Details for Product No. ABIN271659
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Antigen
Reactivity
Rat (Rattus)
(28), (27), (16), (13), (12), (12)
Host
Rabbit
(31), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(21), (11), (10), (7), (4), (2), (1)
Pubmed 4 references available
Quantity 0.1 mL
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Catalog No. ABIN271659
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Immunogen A synthetic peptide (KLHKMSSLSSVGVQILKPSTQF) as part of rat contactin-6
Specificity This antiserum stains beautifully the NB3 in DRG, where it nicely stains a subpopulation of neurons and in the trigeminal nerve root, where staining is restricted to the oligodendrocytes.
Cross-Reactivity (Details) Confirmed to react with rat,Contactin-6.
Purification Whole antisera
Alternative Name Contactin-6
Background Contactin 6 is a member of the immunoglobulin superfamily. It is aglycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein whichfunctions as a cell adhesion molecule. It may play a role in the formation of axonconnections in the developing nervous system. Alternate Names: anti-CNTN 6 antibody, anti-CNTN6 antibody, anti-Contactin 6 precursor antibody,anti-Contactin6 antibody, anti-hNB 3 antibody, anti-hNB3 antibody, anti-MGC133256antibody, anti-NB 3 antibody, anti-NB3 antibody, anti-Neural adhesion moleculeantibody, anti-Neural recognition molecule NB 3 antibody. Related Diseases: Adhesion Molecules
Gene Symbol: CNTN6
Gene ID 27255, 27256
Application Notes Recommended dilutions: Immunohistochemistry-Paraffin 1:1000 to 1: 5000, Immunohistochemistry
Restrictions For Research Use only
Format Lyophilized
Reconstitution Add diH20 to desired concentration.
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
General Kamei, Tsutsumi, Taketani et al.: "cDNA cloning and chromosomal localization of neural adhesion molecule NB-3 in human." in: Journal of neuroscience research, Vol. 51, Issue 3, pp. 275-83, 1998 (PubMed).

Lee, Takeda, Kawano et al.: "Expression and regulation of a gene encoding neural recognition molecule NB-3 of the contactin/F3 subgroup in mouse brain." in: Gene, Vol. 245, Issue 2, pp. 253-66, 2000 (PubMed).

Takeda, Akasaka, Lee et al.: "Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup." in: Journal of neurobiology, Vol. 56, Issue 3, pp. 252-65, 2003 (PubMed).

Cui, Hu, Tekaya et al.: "NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes." in: The Journal of biological chemistry, Vol. 279, Issue 24, pp. 25858-65, 2004 (PubMed).

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