Contactin 6 (CNTN6) antibody

Details for Product No. ABIN271659
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Antigen
Synonyms NB3, NB-3, DKFZp459A015
Reactivity
Rat (Rattus)
(25), (25), (14), (13), (12), (12)
Host
Rabbit
(28), (2), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Immunohistochemistry (Frozen Sections) (IHC (fro))
(17), (12), (10), (6), (4), (2), (1), (1)
Pubmed 4 references available
Catalog no. ABIN271659
Quantity 0.1 mL
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Immunogen A synthetic peptide (KLHKMSSLSSVGVQILKPSTQF) as part of rat contactin-6.
Specificity This antiserum stains beautifully the NB3 in DRG, where it nicely stains a subpopulationof neurons and in the trigeminal nerve root, where staining is restricted to theoligodendrocytes. Species Reactivity: Reacts with rat. Localization: Accession Number: CNTN6_RAT.
Cross-Reactivity Rat (Rattus)
Alternative Name Contactin-6
Background Contactin 6 is a member of the immunoglobulin superfamily. It is aglycosylphosphatidylinositol (GPI)-anchored neuronal membrane protein whichfunctions as a cell adhesion molecule. It may play a role in the formation of axonconnections in the developing nervous system. Alternate Names: anti-CNTN 6 antibody, anti-CNTN6 antibody, anti-Contactin 6 precursor antibody,anti-Contactin6 antibody, anti-hNB 3 antibody, anti-hNB3 antibody, anti-MGC133256antibody, anti-NB 3 antibody, anti-NB3 antibody, anti-Neural adhesion moleculeantibody, anti-Neural recognition molecule NB 3 antibody. Related Diseases: Adhesion Molecules
Gene ID 27255, 27256
Application Notes Suggested working dilutions: immunohistochemistry 1:1000 to 1: 5000
Restrictions For Research Use only
Format Liquid
Buffer Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. Preservative: No Preservative.
Storage 4 °C
General Kamei, Tsutsumi, Taketani et al.: "cDNA cloning and chromosomal localization of neural adhesion molecule NB-3 in human." in: Journal of neuroscience research, Vol. 51, Issue 3, pp. 275-83, 1998 (PubMed).

Lee, Takeda, Kawano et al.: "Expression and regulation of a gene encoding neural recognition molecule NB-3 of the contactin/F3 subgroup in mouse brain." in: Gene, Vol. 245, Issue 2, pp. 253-66, 2000 (PubMed).

Takeda, Akasaka, Lee et al.: "Impaired motor coordination in mice lacking neural recognition molecule NB-3 of the contactin/F3 subgroup." in: Journal of neurobiology, Vol. 56, Issue 3, pp. 252-65, 2003 (PubMed).

Cui, Hu, Tekaya et al.: "NB-3/Notch1 pathway via Deltex1 promotes neural progenitor cell differentiation into oligodendrocytes." in: The Journal of biological chemistry, Vol. 279, Issue 24, pp. 25858-65, 2004 (PubMed).

Hosts (28), (2), (1)
Reactivities (25), (25), (14), (13), (12), (12)
Applications (17), (12), (10), (6), (4), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (12), (8), (1), (1), (1)
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