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Details for Product No. ABIN271662

Autophagy Related 12 (ATG12) antibody

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Antigen
Synonyms APG12, FBR93, APG12L, HAPG12, Apg12l, Atg12l, 4931423H11Rik, A330058M13Rik
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality Polyclonal
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
Pubmed 3 references available
Catalog no. ABIN271662
Quantity 0.5 mg
Price
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Immunogen A synthetic peptide corresponding to the N-terminal of human APG12 protein has beenused as the immunogen. No immunogenic carrier protein was conjugated to theimmunogen. Instead, Adjukine B (see the Adjuvants in biosensis' product list) has beenused to orchestrate/boost the immune response.
Isotype IgG
Specificity IHC and WB confirmed the specificity for APG12. Species Reactivity: Human, rat. Localization: Accession Number: ATG12_HUMAN.
Cross-Reactivity Human, Rat (Rattus)
Alternative Name APG12 / ATG12
Background FUNCTION: Required for autophagy. SUBUNIT: Conjugated to ATG5. SUBCELLULARLOCATION: Cytoplasm. ALTERNATIVE PRODUCTS: 2 named isoforms produced byalternative splicing. TISSUE SPECIFICITY: Ubiquitous. SIMILARITY: Belongs to theATG12 family. Alternate Names: anti-Autophagy-related protein 12 antibody, anti-APG12-like antibody, anti-APG 12,biosensis. GENE NAME: ATG12 antibody, anti-APG12 antibody, anti-APG12L antibody. Related Diseases: Autophagy
Gene ID 9140, 361321
Application Notes IHC, immunofluorescence, WB. A working concentration of 1-5
Restrictions For Research Use only
Buffer Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material. Preservative: No Preservative.
Mizushima, Sugita, Yoshimori et al.: "A new protein conjugation system in human. The counterpart of the yeast Apg12p conjugation system essential for autophagy." in: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 33889-92, 1999 (PubMed).

Tanida, Tanida-Miyake, Komatsu et al.: "Human Apg3p/Aut1p homologue is an authentic E2 enzyme for multiple substrates, GATE-16, GABARAP, and MAP-LC3, and facilitates the conjugation of hApg12p to hApg5p." in: The Journal of biological chemistry, Vol. 277, Issue 16, pp. 13739-44, 2002 (PubMed).

Tanida, Nishitani, Nemoto et al.: "Mammalian Apg12p, but not the Apg12p.Apg5p conjugate, facilitates LC3 processing." in: Biochemical and biophysical research communications, Vol. 296, Issue 5, pp. 1164-70, 2002 (PubMed).

Alternatives for antigen "Autophagy Related 12 (ATG12)", type "Antibodies"
Hosts (78), (8), (5), (1)
Reactivities (75), (44), (40), (13), (13), (13), (5), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Applications (81), (40), (36), (16), (16), (10), (5), (4), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (22), (7), (6), (3), (2), (2), (2), (2), (2), (1), (1), (1), (1)
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