GABA(A) Receptor-Associated Protein-Like 2 (GABARAPL2) (N-Term) antibody

Details for Product No. ABIN271667
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Antigen
Epitope
N-Term
(34), (18), (16), (14), (6), (6), (5), (1), (1), (1), (1), (1)
Reactivity
Human
(146), (25), (25), (2), (1), (1), (1), (1)
Host
Rabbit
(140), (4), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(19), (19), (19), (10), (10), (10), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
(96), (93), (79), (16), (15), (10), (6), (3), (1)
Pubmed 3 references available
Quantity 0.1 mL
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Immunogen A synthetic peptide (CVESAKIRAKYP) corresponding to the N-terminal of human GABARAP L2 (GABARAPL2) protein has been used as the immunogen. The sequence is homologous with mouse and rat form of GABARAP L2 (GABARAPL2).
Cross-Reactivity (Details) Predicted cross-reactivity based on antigen sequence identity: Mouse (100%).
Purification Whole antisera
Alternative Name GABARAPL2 (GABARAPL2 Antibody Abstract)
Background FUNCTION: Involved in intra-Golgi traffic. Modulates intra-Golgi transport throughcoupling between NSF activity and SNAREs activation. It first stimulates the ATPaseactivity of NSF which in turn stimulates the association with GOSR1. SUBUNIT:Monomer. Interacts with GABRG2, NSF, GOSR1 and beta-tubulin. Interacts with ULK1.SUBCELLULAR LOCATION: Golgi apparatus. TISSUE SPECIFICITY: Ubiquitous.Expressed at high levels in the brain, heart, prostate, ovary, spleen and skeletal muscle.Expressed at very low levels in lung, thymus and small intestine. SIMILARITY: Belongsto the MAP1 LC3 family. Alternate Names: anti-Gamma-aminobutyric acid receptor-associated protein-like 2 antibody,anti-GABA(A) receptor-associated protein-like 2 antibody, anti-Ganglioside expressionfactor 2 antibody, anti-GEF-2 antibody, anti-General protein transport factor p16antibody, anti-MAP1 light chain 3-related protein, anti-ATG8 antibody, anti-GATE16antibody, biosensis. GENE NAME: GABARAPL2 antibody, anti-FLC3A antibody,anti-GEF2 antibody. Related Diseases: Autophagy
Gene Symbol: GABARAPL2
Gene ID 11345, 64670
Research Area Cancer
Application Notes Recommended dilutions: Immunocytochemistry/Immunofluorescence 1:200-1:1000, Immunohistochemistry 1:200-1:1000, Western Blot 1:200-1:1000
Restrictions For Research Use only
Format Lyophilized
Buffer Lyophilized serum. Add diH20 to desired concentration.
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
General Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). ..." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Xin, Yu, Chen et al.: "Cloning, expression patterns, and chromosome localization of three human and two mouse homologues of GABA(A) receptor-associated protein." in: Genomics, Vol. 74, Issue 3, pp. 408-13, 2001 (PubMed).

Okazaki, Yan, Yuasa et al.: "Interaction of the Unc-51-like kinase and microtubule-associated protein light chain 3 related proteins in the brain: possible role of vesicular transport in axonal elongation." in: Brain research. Molecular brain research, Vol. 85, Issue 1-2, pp. 1-12, 2001 (PubMed).

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Catalog No. ABIN271667
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