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Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A) antibody

Antigen

Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A)
Synonyms LC3, LC3A, MAP1ALC3, MAP1BLC3, LC3a, 1010001H21Rik, 4922501H04Rik, MGC105263, MGC69006, map1lc3a, MGC53333, zgc:77094, MAP1LC3A, MGC89867, MGC138125
Clonality Polyclonal
Host
Alternatives

Rabbit
Reactivity
Alternatives

Human
Conjugate
Alternatives Un-conjugated
Application
Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (IF), Western Blotting (WB)
1 reference available
Catalog no. ABIN271671
Quantity 0.1 ml  (Variants)
Price Product not available in this region.
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Additional Information
Application Details Publications Alternatives Variants back to top

Alternative name LC3A
Gene ID 84557, 362245
Immunogen A synthetic peptide corresponding to the N-terminal of human MAP1LC3 A proteinconjugated to Blue Carrier Protein has been used as the immunogen. The sequence ishomologous with mouse and rat form of MAP1LC3 A.
Cross-Reactivity Human, Rat (Rattus)
Description FUNCTION: Probably involved in formation of autophagosomal vacuoles(autophagosomes). SUBUNIT: 3 different light chains, LC1, LC2 and LC3, can associatewith MAP1A and MAP1B proteins. SUBCELLULAR LOCATION: LC3-I: Cytoplasm.LC3-II: Intracytoplasmic membrane, lipid-anchor. LC3-II binds to the autophagicmembranes. PTM: The precursor molecule is cleaved by APG4B/ATG4B to form thecytosolic form, LC3-I. This is activated by APG7L/ATG7, transferred to ATG3 andconjugated to phospholipid to form the membrane-bound form, LC3-II. SIMILARITY:Belongs to the MAP1 LC3 family. Alternate Names: anti-Microtubule-associated proteins 1A/1B light chain 3A antibody, anti-MAP1A/MAP1BLC3 A antibody, anti-MAP1A/1B light chain 3 A antibody, anti-MAP1 light chain 3-likeprotein 1 antibody, anti-Microtubule-associated protein 1 light chain 3 alpha antibody,anti-Autophagy-related protein LC3 A antibody, anti-Autophagy-related ubiquitin-likemodifier LC3 A antibody, anti-APG8a, biosensis. GENE NAME: MAP1LC3A antibody. Related Diseases: Autophagy
Specificity IHC, WB and ELISA confirmed the specificity for MAP1LC3 A (MAP1LC3A, APG8a). Species Reactivity: Human, rat. Other species not yet tested. Localization: Accession Number: MLP3A_HUMAN , MLP3A_MOUSE , MLP3A_RAT.

Application Details
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Application Notes IHC, immunofluorescence, WB. A dilution of 1:100 to 1:1000 dilution is recommendedfor these applications. The optimal dilution should be determined by the end user.
Buffer Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. Preservative: No Preservative.
Restrictions For Research Use only

Publications
Application Details Alternatives Variants back to top

Gerhard, Wagner, Feingold et al.: "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)." in: Genome research, Vol. 14, Issue 10B, pp. 2121-7, 2004 (PubMed).

Alternatives
Application Details Publications Variants back to top

Alternatives for antigen "Microtubule-Associated Protein 1 Light Chain 3 alpha (MAP1LC3A)", type "Antibodies"
Hosts Rabbit (47), Sheep (4), Goat (2), Mouse (2)
Reactivities Human (50), Mouse (Murine) (29), Rat (Rattus) (27), Cow (Bovine) (11), Dog (Canine) (4), Opossum (Didelphimorphia) (3), Chicken (2), Pig (Porcine) (2), Zebrafish (2), Cat (Feline) (1), Fish (1), Monkey (1), Rabbit (1), Xenopus laevis (1), Zebrafish (Danio rerio) (1)
Applications Western Blotting (WB) (45), ELISA (23), Immunofluorescence (IF) (19), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) (15), Immunohistochemistry (IHC) (10), Immunocytochemistry (ICC) (8), Immunoprecipitation (IP) (5), Dot Blot (DB) (2), Dot Blot (Dot) (2), Immunohistochemistry (Fixed) (IHC (fx)) (1)
Conjugates Alexa Fluor 350 (1), Alexa Fluor 488 (1), Alexa Fluor 555 (1), Alexa Fluor 647 (1), PE,Cy5.5 (1)
Epitopes pSer12 (4), N-Term (3), AA 1-50 (2), AA 97-106 (1), Cleaved (1), Internal Region (1), pSer3 (1), pThr93 (1), pTyr182,pThr180 (1)