Trpl (trpl) antibody

Antigen: Trpl (trpl)

Synonyms: CG1694, CG18345, DmelCG18345, DmTRPL, dTrpL, dTRPL, trp-l, TrpL, TRPL

Clonality: Polyclonal

Host: Rabbit

Application: Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)

Catalog no.: ABIN271672

Additional Information

Alternative name: TRPL

Immunogen: A synthetic peptide (C-DNSNFDIH VVDLDEK) as part of Drosophila TRPL protein (aa:1083-1097) conjugated to Diphtheria toxoid.

Description: TRPL is a light-sensitive calcium channel that is required for inositide-mediated Ca(2+)entry in the retina during phospholipase C (PLC)-mediated phototransduction. It isrequired for vision in the dark and in dim light and binds calmodulin. Trp and TRPL acttogether in the light response, although it is unclear whether as heteromultimers ordistinct units. TRPL also forms a functional cation channel with trp-gamma and isactivated by fatty acids, metabolic stress, inositols and GTP-binding proteins. Alternate Names: anti-Transient-receptor-potential-like protein antibody. Related Diseases: TRP channels

Specificity: This antiserum detects TRPL in Drosophila and transiently expressed recombinantTRPL. Species Reactivity: Reacts with Drosophila. Localization: Accession Number: TRPL_DROME.

Application Details

Application Notes: Suggested working dilutions: immunohistochemistry 1 u/ml,Western Blot 1 u/ml

Buffer: Reconstitute in 20 ul of sterile water. Centrifuge to remove any insoluble material. Preservative: No Preservative.

Storage: Store at 4C short term. Aliquot and store at -20 long term. Avoid freeze-thaw cycles.

Research Area: Neurology

Restrictions: For Research Use only

Publications

Niemeyer, Suzuki, Scott et al.: "The Drosophila light-activated conductance is composed of the two channels TRP and TRPL." in: Cell, Vol. 85, Issue 5, pp. 651-9, 1996 (PubMed).