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Trpl (trpl) antibody

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Fruit Fly (Drosophila melanogaster)
Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(6), (4)
Pubmed 1 reference available
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Quantity 0.02 mg
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Immunogen A synthetic peptide (C-DNSNFDIH VVDLDEK) as part of Drosophila TRPL protein (aa: 1083-1097) conjugated to Diphtheria toxoid
Specificity This antiserum detects TRPL in Drosophila and transiently expressed recombinant TRPL.
Purification Affinity purified
Alternative Name TRPL (trpl Antibody Abstract)
Background TRPL is a light-sensitive calcium channel that is required for inositide-mediated Ca(2+)entry in the retina during phospholipase C (PLC)-mediated phototransduction. It isrequired for vision in the dark and in dim light and binds calmodulin. Trp and TRPL acttogether in the light response, although it is unclear whether as heteromultimers ordistinct units. TRPL also forms a functional cation channel with trp-gamma and isactivated by fatty acids, metabolic stress, inositols and GTP-binding proteins. Alternate Names: anti-Transient-receptor-potential-like protein antibody. Related Diseases: TRP channels
Research Area Neurology
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 20 µL of sterile water. Centrifuge to remove any insoluble material.
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
General Niemeyer, Suzuki, Scott et al.: "The Drosophila light-activated conductance is composed of the two channels TRP and TRPL." in: Cell, Vol. 85, Issue 5, pp. 651-9, 1996 (PubMed).

Catalog No. ABIN271672

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