Did you know that you can buy products from over 140 different suppliers from us?

ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) (C-Term) antibody

Details for Product No. ABIN271681
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Epitope
C-Term
(14), (12), (9), (8), (7), (6), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(90), (34), (19), (16), (14), (14), (3), (3), (2), (2), (1)
Host
Rabbit
(87), (3), (1)
Clonality
Polyclonal
Conjugate
Un-conjugated
(4), (4), (4), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC)
(69), (32), (30), (20), (16), (2), (2), (2), (1)
Pubmed 1 reference available
Quantity 0.1 mL
Shipping to United States (Change)
Catalog No. ABIN271681
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen A synthetic peptide (CLERFFDSEDED) corresponding to the C-terminus of human ATG4B protein conjugated to Blue Carrier Protein has been used as the immunogen.
Specificity IHC, WB and ELISA confirmed the specificity for ATG4B.
Cross-Reactivity (Details) The peptide is homologous with the corresponding sequence derived from of ATG4B protein in mouse,rat.
Purification IgG purified
Alternative Name APG4B / ATG4B
Background FUNCTION: Cysteine protease required for autophagy, which cleaves the C-terminalpart of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. Asubpopulation of form I is subsequently converted to a smaller form (form II). Form II,with a revealed C-terminal glycine, is considered to be the phosphatidylethanolamine(PE)-conjugated form, and has the capacity for the binding to autophagosomes.ENZYME REGULATION: Inhibited by N-ethylmaleimide. SUBCELLULAR LOCATION:Cytoplasm (Probable). ALTERNATIVE PRODUCTS: 5 named isoforms produced byalternative splicing. Alternate Names: anti-Cysteine protease ATG4B antibody, anti-Autophagy-related protein 4 homolog Bantibody, anti-hAPG4B antibody, anti-Autophagin-1 antibody, anti-Autophagy-relatedcysteine endopeptidase 1 antibody, anti-AUT-like 1 cysteine endopeptidase, biosensis.GENE NAME: ATG4B antibody, anti-APG4B antibody, anti-AUTL1 antibody,anti-KIAA0943 antibody. Related Diseases: Autophagy
Gene Symbol: ATG4B
Gene ID 23192, 316640
Application Notes Recommended dilutions: ELISA, Immunocytochemistry/Immunofluorescence 1:100-1:2000, Immunohistochemistry 1:100-1:2000, Western Blot 1:100-1:2000
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of sterile water.
Buffer Lyophilized whole serum.
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
General Mariño, Uría, Puente et al.: "Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy." in: The Journal of biological chemistry, Vol. 278, Issue 6, pp. 3671-8, 2003 (PubMed).

Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN271681
Contact our Customer Service for availability and price in your country.
Add to Basket

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Validation Images
Did you look for something else?
back to top