ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) (N-Term) antibody

Details for Product No. ABIN271682
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Antigen
Epitope
N-Term
(22), (20), (16), (14), (12), (12), (12), (12), (5), (4), (3), (3), (3), (3), (2), (2), (2), (1), (1), (1), (1), (1)
Reactivity
Human
(165), (75), (54), (12), (10), (5), (4), (2), (2), (2), (2), (1), (1)
Host
Rabbit
(138), (21), (17), (2)
Clonality
Polyclonal
Conjugate
Un-conjugated
(8), (8), (7), (5), (5), (5), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2)
Application
Western Blotting (WB), ELISA, Immunocytochemistry (ICC), Immunofluorescence (IF), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
(135), (64), (36), (26), (20), (15), (15), (8), (6), (5), (4), (3), (3), (1)
Pubmed 3 references available
Quantity 0.1 mL
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Immunogen N-terminal of human ATG16-L1 protein conjugated to Blue Carrier Protein has been used as the immunogen.
Specificity IHC, WB and ELISA confirmed the specificity for ATG16 L1.
Cross-Reactivity (Details) Other species not yet tested.
Purification Whole antisera
Alternative Name APG16L / ATG16L1 (ATG16L1 Antibody Abstract)
Background FUNCTION: Plays an essential role in autophagy. SUBUNIT: Homooligomer. Interactswith ATG5. Part of either the minor and major complexes respectively composed of 4sets of ATG12-ATG5 and ATG16L1 (400 kDa) or 8 sets of ATG12-ATG5 and ATG16L1(800 kDa). SUBCELLULAR LOCATION: Cytoplasm. Preautophagosomal structure,preautophagosomal structure membrane, peripheral membrane protein. Localized topreautophagosomal structure (PAS) where it is involved in the membrane targeting ofATG5. ALTERNATIVE PRODUCTS: 5 named isoforms produced by alternative splicing.SIMILARITY: Belongs to the WD repeat ATG16 family. SIMILARITY: Contains 7 WDrepeats. Alternate Names: biosensis. Related Diseases: Autophagy
Gene Symbol: ATG16L1
Gene ID 55054, 363278
Application Notes Recommended dilutions: Western Blot 1:100-1:3000, ELISA, Immunocytochemistry/Immunofluorescence 1:100-1:3000, Immunohistochemistry, Immunohistochemistry-Paraffin
Restrictions For Research Use only
Format Lyophilized
Reconstitution Reconstitute in 100 µL of purified water.
Preservative Without preservative
Handling Advice Avoid freeze-thaw cycles
Storage 4 °C
Storage Comment 4 °C short term. Aliquot and store at -20 °C long term.
General Zheng, Ji, Li et al.: "Cloning and analysis of human Apg16L." in: DNA sequence : the journal of DNA sequencing and mapping, Vol. 15, Issue 4, pp. 303-5, 2004 (PubMed).

Ota, Suzuki, Nishikawa et al.: "Complete sequencing and characterization of 21,243 full-length human cDNAs. ..." in: Nature genetics, Vol. 36, Issue 1, pp. 40-5, 2003 (PubMed).

Clark, Gurney, Abaya et al.: "The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment. ..." in: Genome research, Vol. 13, Issue 10, pp. 2265-70, 2003 (PubMed).

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Catalog No. ABIN271682
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