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Details for Product No. ABIN271688

Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1) antibody

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Synonyms ADTG, CLAPG1, Adtg, AA409002, AU041323, AW551707, D8Ertd374e, adtg, zgc:56079, wu:fc30a11, AP1G1, ap1g1
»Alternatives Human
»Alternatives Rabbit
Clonality Polyclonal
»Alternatives Un-conjugated
»Alternatives Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
Pubmed 5 references available
Catalog no. ABIN271688
Quantity 0.1 mL
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Immunogen A synthetic peptide (IRLRELIRTIRTARTQAEER) corresponding to the amino acids 5-24of human AP-1 complex subunit gamma-1 conjugated to diphtheria toxin has been usedas the immunogen. The peptide is homologous with the corresponding sequencederived from AP-1 complex subunit gamma-1 protein in mouse, rat, dog and zebra fish.
Specificity This antibody has been shown to be specific for AP-1 complex subunit gamma-1. Species Reactivity: Reacts with Rat and human. Localization: Accession Number: AP1G1_HUMAN , AP1G1_MOUSE , AP1G1_RAT , AP1G1_DOG ,AP1G1_ZEBRA FISH.
Cross-Reactivity Human, Rat (Rattus)
Alternative Name AP1 complex subunit gamma-1
Background Adaptins are important components of clathrin-coated vesicles transportingligand-receptor complexes from the plasma membrane or from the trans-Golgi networkto lysosomes. The adaptin family of proteins is composed of four classes of moleculesnamed alpha, beta, beta prime and gamma adaptins. Adaptins, together with mediumand small subunits, form a heterotetrameric complex called an adaptor, whose role is topromote the formation of clathrin-coated pits and vesicles. The protein encoded by thisgene is a gamma-adaptin protein and it belongs to the adaptor complexes largesubunits family. Alternate Names: anti-Adapter-related protein complex 1 gamma-1 subunit Gamma-adaptin antibody,anti-Adaptor protein complex AP-1 gamma-1 subunit antibody, anti-Golgi adaptorHA1/AP1 adaptin subunit gamma-1 antibody, anti-Clathrin assembly protein complex 1gamma-1 large chain antibody, anti-GENE NAME: AP1G1 antibody, anti-ADTGantibody, anti-CLAPG1 antibody. Related Diseases: Intracellular Trafficking
Gene ID 164, 171494
Application Notes Suggested working dilutions: immunohistochemistry 1: 200 to 1: 2000,Western Blot 1: 1000 to 1: 4000
Restrictions For Research Use only
Buffer Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material. Preservative: No Preservative.
Storage 4 °C
Robinson: "Cloning and expression of gamma-adaptin, a component of clathrin-coated vesicles associated with the Golgi apparatus." in: The Journal of cell biology, Vol. 111, Issue 6 Pt 1, pp. 2319-26, 1991 (PubMed).

Peyrard, Parveneh, Lagercrantz et al.: "Cloning, expression pattern, and chromosomal assignment to 16q23 of the human gamma-adaptin gene (ADTG)." in: Genomics, Vol. 50, Issue 2, pp. 275-80, 1998 (PubMed).

Takatsu, Sakurai, Shin et al.: "Identification and characterization of novel clathrin adaptor-related proteins." in: The Journal of biological chemistry, Vol. 273, Issue 38, pp. 24693-700, 1998 (PubMed).

Nogi, Shiba, Kawasaki et al.: "Structural basis for the accessory protein recruitment by the gamma-adaptin ear domain." in: Nature structural biology, Vol. 9, Issue 7, pp. 527-31, 2002 (PubMed).

Deneka, Neeft, Popa et al.: "Rabaptin-5alpha/rabaptin-4 serves as a linker between rab4 and gamma(1)-adaptin in membrane recycling from endosomes." in: The EMBO journal, Vol. 22, Issue 11, pp. 2645-57, 2003 (PubMed).

Alternatives for antigen "Adaptor-Related Protein Complex 1, gamma 1 Subunit (AP1G1)", type "Antibodies"
Hosts (40), (11), (8)
Reactivities (48), (37), (34), (30), (28), (28), (24), (1), (1), (1), (1)
Applications (34), (20), (19), (12), (7), (6), (3), (2), (1), (1)
Conjugates (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (2), (1), (1)
Epitopes (4), (2), (2), (1), (1), (1)