KCNC2 antibody

Catalog No. ABIN271788

Product Details anti-KCNC2 Antibody

Target: KCNC2 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 2 (KCNC2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNC2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of Potassium Channel Kv3.2b/Kcnc2 protein. (region surrounding Pro626)

Cross-Reactivity (Details): Species reactivity (expected):Mouse and Rat.
Species reactivity (tested):Human.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000. IHC: 1: 50approx. 1: 200.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE!

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for KCNC2

Target: KCNC2 (Potassium Voltage-Gated Channel, Shaw-Related Subfamily, Member 2 (KCNC2))

Alternative Name: KCNC2 (KCNC2 Products)

Synonyms: KV3.2 antibody, KShIIIA antibody, Kv3.2 antibody, AW047325 antibody, B230117I07 antibody, KCNC2 antibody, zgc:162956 antibody, potassium voltage-gated channel subfamily C member 2 antibody, potassium voltage gated channel, Shaw-related subfamily, member 2 antibody, potassium voltage-gated channel, Shaw-related subfamily, member 2 antibody, potassium channel, voltage gated Shaw related subfamily C, member 2 antibody, KCNC2 antibody, Kcnc2 antibody, kcnc2 antibody

Background: Potassium channels contribute to maintaining cell volume, membrane potential, neuronal excitability and the secretion of transmitters, salt and hormones. Two families of potassium channels have been identified. One family includes the inwardly rectifying potassium channels whereas, the other family includes: voltage sensing (KV), big conductance, calcium activated (BKca), and small conductance, calcium activated (SK) potassium channels. Kv3.2 functions as a delayed rectifier type K+ channel activated by large membrane depolarizations.Synonyms: Potassium voltage-gated channel subfamily C member 2, Voltage-gated potassium channel Kv3.2

Molecular Weight: approx. 70 kDa

Gene ID: 3747

NCBI Accession: NP_631874

UniProt: Q96PR1