COL3A1
Reactivity: Human, Mouse, Rat, Cow, Dog, Pig, Rabbit
WB, IHC, IF, IC
Host: Rabbit
Polyclonal
unconjugated
Application Notes
ELISA: 1/10000approx. 1/20000. Immunoflourescence: 1/50approx. 1/200. Immunohistochemistry: 1/50approx. 1/200. Other applications not tested. Optimal dilutions are dependent on conditions and should be determined by the user.
Restrictions
For Research Use only
Concentration
1.0 mg/mL
Buffer
PBS, pH ~7.2, 0.05 % Sodium Azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
4 °C/-20 °C
Storage Comment
Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
Xie, Dolder, Siegrist, Wetterwald, Hofstetter: "Glutamate Receptor Agonists and Glutamate Transporter Antagonists Regulate Differentiation of Osteoblast Lineage Cells." in: Calcified tissue international, Vol. 99, Issue 2, pp. 142-54, (2018) (PubMed).
Schminke, Frese, Bode, Goldring, Miosge: "Laminins and Nidogens in the Pericellular Matrix of Chondrocytes: Their Role in Osteoarthritis and Chondrogenic Differentiation." in: The American journal of pathology, Vol. 186, Issue 2, pp. 410-8, (2016) (PubMed).
Chen, Yang, Huang, Pan, Liu, Qiu: "Angiotensin-(1-7) attenuates lung fibrosis by way of Mas receptor in acute lung injury." in: The Journal of surgical research, Vol. 185, Issue 2, pp. 740-7, (2013) (PubMed).
Xie, Li, Wang, Zhang, Peng, Yang, Zou, Ge, Chen, Chen: "In vivo delivery of adenoviral vector containing interleukin-17 receptor a reduces cardiac remodeling and improves myocardial function in viral myocarditis leading to dilated cardiomyopathy." in: PLoS ONE, Vol. 8, Issue 8, pp. e72158, (2013) (PubMed).
Zhang, Shen, Zhang, Wan, Yao, Wu, Wang, Chen, Yan, Jiang: "Induction of thoracic aortic remodeling by endothelial-specific deletion of microRNA-21 in mice." in: PLoS ONE, Vol. 8, Issue 3, pp. e59002, (2013) (PubMed).
EDS4A antibody, AW550625 antibody, Col3a-1 antibody, MMS10-W antibody, Ms10w antibody, mKIAA4231 antibody, col3a1 antibody, collagen type III alpha 1 chain antibody, collagen, type III, alpha 1 antibody, collagen, type III, alpha 1 (Ehlers-Danlos syndrome type IV, autosomal dominant) S homeolog antibody, COL3A1 antibody, Col3a1 antibody, col3a1 antibody, col3a1.S antibody
Background
Collagen III is a fibrillar collagen that is found in extensible connective tissues such as skin, lung, and the vascular system, frequently in association with type I Collagen. Mutations in the gene are associated with Ehlers Danlos syndrome type IV, and with aortic and arterial aneurysms. Although alternate transcripts have been detected for this gene, they are the result of mutations, these mutations alter splicing, often leading to the exclusion of multiple exons.Synonyms: COL3A1