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MMP10 antibody

MMP10 Reactivity: Human, Mouse, Rat IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN272036
  • Target See all MMP10 Antibodies
    MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))
    Reactivity
    Human, Mouse, Rat
    Host
    • 58
    • 9
    Rabbit
    Clonality
    • 60
    • 7
    Polyclonal
    Conjugate
    • 35
    • 9
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This MMP10 antibody is un-conjugated
    Application
    • 48
    • 30
    • 28
    • 12
    • 8
    • 7
    • 5
    • 4
    • 2
    • 1
    • 1
    Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of MMP-10 protein. (region surrounding Ile387)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen
    Top Product
    Discover our top product MMP10 Primary Antibody
  • Application Notes
    ELISA: 1: 20000approx. 1: 40000. IF: 1: 50approx. 1: 200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH ~7.2, 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    MMP10 (Matrix Metallopeptidase 10 (Stromelysin 2) (MMP10))
    Alternative Name
    MMP-10 (MMP10 Products)
    Synonyms
    SL-2 antibody, STMY2 antibody, AV377895 antibody, MMP-10 antibody, matrix metallopeptidase 10 antibody, MMP10 antibody, Mmp10 antibody
    Background
    Proteins of the matrix metalloproteinase (MMP) family are zinc containing proteolytic enzymes involved in the breakdown of the extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling. They also play an important role in apoptosis, tumor cell growth, invasion, metastasis, as well as in angiogenesis and wound healing. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. Most of the MMP's contain a common domain structure, which include a signal sequence, a propeptide, a catalytic domain and a hemopexin-like (Hpx) domain. MMP10 degrades proteoglycans, gelatins of type I, III, IV, and V, weakly collagens III, IV, and V. and fibronectin. It activates procollagenase. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.Synonyms: MMP10, Matrix metalloproteinase-10, SL-2, STMY2, Stromelysin-2, Transin-2
    Molecular Weight
    approx. 54 kDa
    Gene ID
    4319
    NCBI Accession
    NP_002416
    UniProt
    P09238
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