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DLGAP1 antibody

DLGAP1 Reactivity: Human, Mouse, Rat WB, IF, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN272131
  • Target See all DLGAP1 Antibodies
    DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))
    Reactivity
    • 48
    • 16
    • 16
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 35
    • 11
    • 2
    • 1
    Rabbit
    Clonality
    • 38
    • 11
    Polyclonal
    Conjugate
    • 21
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This DLGAP1 antibody is un-conjugated
    Application
    • 18
    • 13
    • 13
    • 12
    • 9
    • 8
    • 8
    • 3
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of SAPAP1 protein. (region surrounding Glu817)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Purity
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product DLGAP1 Primary Antibody
  • Application Notes
    ELISA: 1: 5000approx. 1: 10000. Western blot: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2, 0.05 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    DLGAP1 (Discs, Large (Drosophila) Homolog-Associated Protein 1 (DLGAP1))
    Alternative Name
    DLGAP1 / SAPAP1 (DLGAP1 Products)
    Synonyms
    DKFZp469D0713 antibody, gkap antibody, sapap1 antibody, DAP-1 antibody, DAP-1-ALPHA antibody, DAP-1-BETA antibody, GKAP antibody, SAPAP1 antibody, hGKAP antibody, 4933422O14Rik antibody, 9630002F18 antibody, AI845682 antibody, AI848168 antibody, BB075781 antibody, D17Bwg0511e antibody, GKAP/SAPAP antibody, GKPA/SAPAP antibody, Gkap antibody, Sapap1 antibody, mKIAA4162 antibody, DLG associated protein 1 antibody, discs, large (Drosophila) homolog-associated protein 1 antibody, disks large-associated protein 1 antibody, discs, large homolog-associated protein 1 antibody, discs, large (Drosophila) homolog-associated protein 1b antibody, DLGAP1 antibody, LOC100408093 antibody, LOC100548434 antibody, dlgap1 antibody, Dlgap1 antibody, dlgap1b antibody
    Background
    Members of the postsynaptic density-95 (PSD-95)/SAP90 family of membraneassociated guanylate kinase (MAGUK) proteins function as multimodular scaffolds that organize protein-signaling complexes at neuronal synapses. PSD-95/SAP90 binds guanylate kinase-associated protein (GKAP), also designated GK domain-binding protein, DAP-1-α, DAP-1-β, PSD-95 binding protein, PSD-95/SAP90 associated protein, or SAPAP1, through the guanylate kinase domain. SAPAP1 is expressed widely in neurons of the cortex and hippocampus and in the Purkinje and granule cells of the cerebellum. N-terminal splice variants of SAPAP1 are expressed as 95 and 130 kDa proteins. SAPAP1 is localized specifically in the PSD of glutamatergic synapses, consistent with its direct interaction with PSD-95 family proteins.Synonyms: DAP-1, DAP1, Disks large-associated protein 1, GKAP, Guanylate kinase-associated protein, PSD-95/SAP90-binding protein 1, SAP90/PSD-95-associated protein 1
    Molecular Weight
    approx. 108 kDa
    Gene ID
    9229
    NCBI Accession
    NP_001003809
    UniProt
    O14490
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