HOXB9 antibody
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- Target See all HOXB9 Antibodies
- HOXB9 (Homeobox B9 (HOXB9))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This HOXB9 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Specificity
- This antibody detects endogenous levels of Hox-B9 protein. (region surrounding Arg237)
- Cross-Reactivity (Details)
- Species reactivity (tested):Human, Mouse.
- Purification
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
- Purity
- > 95 % pure by SDS-PAGE
- Top Product
- Discover our top product HOXB9 Primary Antibody
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- Application Notes
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ELISA: 1: 10000approx. 1: 20000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user. - Restrictions
- For Research Use only
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- Concentration
- 1,0 mg/mL
- Buffer
- Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- DO NOT FREEZE!
- Storage
- 4 °C
- Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- Target
- HOXB9 (Homeobox B9 (HOXB9))
- Alternative Name
- HOXB9 / HOX2E (HOXB9 Products)
- Synonyms
- HOX-2.5 antibody, HOX2 antibody, HOX2E antibody, Hox-2.5 antibody, BZ-23 antibody, bz23 antibody, hoxb9 antibody, wu:fc06b03 antibody, hox2 antibody, hox2e antibody, xhoxb9 antibody, hox-2.5 antibody, MGC75797 antibody, HOXB9 antibody, HoxB9a antibody, homeobox B9 antibody, homeobox B9a antibody, homeo box B9 antibody, HOXB9 antibody, Hoxb9 antibody, hoxb9a antibody, hoxb9 antibody
- Background
- The Hox proteins play a role in development and cellular differentiation by regulating downstream target genes. Specifically, the Hox proteins direct DNA-protein and protein-protein interactions that assist in determining the morphologic features associated with the anterior-posterior body axis. Themammalian Hox gene complex consists of 39 genes that are located on four linkage groups, which are dispersed over four chromosomes. Hox genes that occupy the same relative position along the 5' to 3' coordinate (trans-paralogous genes) are more similar in sequence and expression pattern than adjacent Hox genes on the same chromosome. In mice, the HoxB cluster contains HoxB1 to HoxB9 and HoxB13, which are transcribed in the same direction. HoxB9 associates with the transcriptional cofactors BTG1 and BTG2, which enhance HoxB9 ranscription. Alterations in HoxB9 expression, as with other Hox family member, has been implicated in leukemia.Synonyms: Homeobox protein Hox-B9, Hox-2.5, Hox-2E
- Molecular Weight
- approx. 28 kDa
- Gene ID
- 3219
- NCBI Accession
- NP_076922
- UniProt
- P17482
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