Recoverin antibody

Catalog No. ABIN272183

Product Details anti-Recoverin Antibody

Target: Recoverin (RCVRN)

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Recoverin antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody detects endogenous levels of Recoverin protein. (region surrounding Asp143)

Cross-Reactivity (Details): Species reactivity (tested):Human and Mouse.

Purification: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Purity: > 95 % pure by SDS-PAGE

Application Details

Application Notes: ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
Other applications not tested.
Optimal dilutions are dependent on conditions and should be determined by the user.

Restrictions: For Research Use only

Handling

Concentration: 1,0 mg/mL

Buffer: Phosphate buffered saline (PBS), pH 7.2., 0.05 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: DO NOT FREEZE!

Storage: 4 °C

Storage Comment: Store the antibody undiluted at 2-8 °C.

Target Details for Recoverin

Target: Recoverin (RCVRN)

Alternative Name: Recoverin (RCVRN Products)

Synonyms: RCV1 antibody, CAR antibody, S-modulin antibody, Rcv1 antibody, rcv1 antibody, rcvrn antibody, recoverin antibody, reco antibody, recoverin antibody, recoverin, gene 2 S homeolog antibody, recoverin, gene 2 L homeolog antibody, Recoverin antibody, RCVRN antibody, Rcvrn antibody, rcvrn.2.S antibody, rcvrn.2.L antibody, reco antibody

Background: The catenins, α, β and γ, are proteins which bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin. Together, the catenin/cadherin complexes play an important role mediating cellular adhesion. α-catenin was initially described as an E-cadherin associated protein, and since has been shown to associate with other members of the cadherin family, such as N-cadherin and P-cadherin. β-catenin associates with the cytoplasmic portion of E-cadherin, which is necessary for the function of E-cadherin as an adhesion molecule. β-catenin has also been found in complexes with the tumor suppressor protein APC. γ-catenin, also known as plakoglobin, is a protein that binds with α-catenin and N-cadherin. It has been shown that the transmembrane phosphatase PTPμ associates with catenin/cadherin complexes and may regulate complex signaling.Synonyms: Cancer-associated retinopathy protein, Protein CAR, RCV1, RCVRN

Molecular Weight: approx. 23 kDa

Gene ID: 5957

NCBI Accession: NP_002894

UniProt: P35243

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Phototransduction