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CEBPE antibody

CEBPE Reactivity: Human, Rat, Mouse WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN272237
  • Target See all CEBPE Antibodies
    CEBPE (CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE))
    Reactivity
    Human, Rat, Mouse
    Host
    • 56
    • 4
    Rabbit
    Clonality
    • 57
    • 3
    Polyclonal
    Conjugate
    • 26
    • 6
    • 4
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    This CEBPE antibody is un-conjugated
    Application
    • 34
    • 28
    • 11
    • 8
    • 4
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of C/EBP-epsilon protein. (region surrounding Lys220)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    Affinity Chromatography using epitope-specific immunogen.
    Top Product
    Discover our top product CEBPE Primary Antibody
  • Application Notes
    ELISA: 1/10000approx. 1/20000. Western blot: 1/500approx. 1/1000. Immunohistochemistry: 1/50 - 1/200.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 0.05 % Sodium Azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C for one month or (in aliquots) at -20 °C for longer.
  • Target
    CEBPE (CCAAT/enhancer Binding Protein (C/EBP), epsilon (CEBPE))
    Alternative Name
    CEBPE (CEBPE Products)
    Synonyms
    CEBPE antibody, crp1 antibody, C/EBP-epsilon antibody, CRP1 antibody, C/EBPe antibody, Gm294 antibody, C/EPBe antibody, CCAAT/enhancer binding protein epsilon antibody, CCAAT/enhancer binding protein (C/EBP), epsilon antibody, CEBPE antibody, cebpe antibody, Cebpe antibody
    Background
    The transcription factor C/EBP alpha (CCAAT-enhancer binding protein) is a heatstable, sequence-specific DNA-binding protein first purified from rat liver nuclei that binds avidly to several different cis-regulatory DNA sequences commonly associated with viral and cellular genes transcribed by RNA polymerase II. C/EBP alpha regulates gene expression in a variety of tissues including liver, adipose, lung and intestine. C/EBP alpha uses a bipartite structural motif to bind DNA. Two protein chains dimerize through a set of amphipathic alpha helices termed the leucine zipper. Highly basic polypeptide regions emerge from the zipper to form a linked set of DNA contact surfaces. C/EBP alpha appears to function exclusively in terminally differentiated, growth-arrested cells. Additional family members include C/EBP beta, C/EBP gamma,C/EBP delta and C/EBP epsilon, all of which exhibit similar DNA-binding specificities and affinities to C/EBP alpha. Furthermore, C/EBP beta and C/EBP delta readily form heterodimers both with each other as well as with C/EBP alpha.Synonyms: C/EBP epsilon, CCAAT/enhancer-binding protein epsilon
    Molecular Weight
    approx. 30 kDa
    Gene ID
    1053
    NCBI Accession
    NP_001796
    UniProt
    Q15744
    Pathways
    Cellular Response to Molecule of Bacterial Origin
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