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Septin 1 antibody

SEPT1 Reactivity: Human, Mouse, Rat WB, IHC (p) Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN272245
  • Target See all Septin 1 (SEPT1) Antibodies
    Septin 1 (SEPT1)
    Reactivity
    • 57
    • 33
    • 17
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Human, Mouse, Rat
    Host
    • 52
    • 4
    • 1
    Rabbit
    Clonality
    • 55
    • 2
    Polyclonal
    Conjugate
    • 25
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This Septin 1 antibody is un-conjugated
    Application
    • 50
    • 24
    • 13
    • 13
    • 6
    • 5
    • 4
    • 3
    • 2
    • 2
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Specificity
    This antibody detects endogenous levels of Septin 1 protein. (region surrounding Asp205)
    Cross-Reactivity (Details)
    Species reactivity (expected):Mouse and Rat.
    Species reactivity (tested):Human.
    Purification
    The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
    Purity
    > 95 % pure by SDS-PAGE
    Top Product
    Discover our top product SEPT1 Primary Antibody
  • Application Notes
    ELISA: 1: 20000approx. 1: 40000. WB: 1: 500approx. 1: 1000.
    Other applications not tested.
    Optimal dilutions are dependent on conditions and should be determined by the user.
    Restrictions
    For Research Use only
  • Concentration
    1,0 mg/mL
    Buffer
    Phosphate buffered saline (PBS), pH 7.2., 15 mM sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    DO NOT FREEZE!
    Storage
    4 °C
    Storage Comment
    Store the antibody undiluted at 2-8 °C.
  • Target
    Septin 1 (SEPT1)
    Alternative Name
    Septin-1 (SEPT1) (SEPT1 Products)
    Synonyms
    DIFF6 antibody, LARP antibody, PNUTL3 antibody, SEP1 antibody, CG1403 antibody, Diff6 antibody, Dmel\\CG1403 antibody, anon-19Fa antibody, iby antibody, sep1 antibody, tu1 antibody, Pnutl3 antibody, SEPT1 antibody, Septin-1 antibody, septin 1 antibody, Septin 1 antibody, pfam02452; PemK antibody, SEPT1 antibody, Sep1 antibody, Sept1 antibody, sepT1 antibody
    Background
    The septins are a family of GTPase enzymes, some of which are required for cytokinesis and others of which are associated with exocytosis. Members of the septin family can form heteropolymer complexes and also play a role in the organization of new growth in organisms. The transcriptional regulation of all septins is complex, resulting in alternatively spliced variants. At least three septins (Septin 1, 2 and 4) are associated with a Tau-based paired helical filament core and may contribute to the formation of neurofibrillary tangle as integral constituents of paired helical filaments. Septin 3 (G-Septin), a GTP-binding protein, is highly expressed in brain and is regulated by protein kinase G in neurons. The human SEPT4 (H5/PNUTL2/CDCrREL-2) gene encodes ARTS (for apoptosis-related protein in the TGFβ signaling pathway), which is expressed in many cells and acts to enhance cell death induced by TGFβ or, to a lesser extent, by other apoptotic agents. ARTS is localized to mitochondria and translocates to the nucleus when apoptosis occurs.Synonyms: DIFF6, LARP, NY-BR-24, PNUTL3, Peanut-like protein 3, Serologically defined breast cancer antigen NY-BR-24
    Molecular Weight
    approx. 40 kDa
    Gene ID
    1731
    NCBI Accession
    NP_443070
    UniProt
    Q8WYJ6
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