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SP1 antibody (Middle Region)

SP1 Reactivity: Human, Mouse, Rat, Cow, Pig, Dog, Goat, Rabbit, Guinea Pig WB Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN2773827
  • Target See all SP1 Antibodies
    SP1 (Sp1 Transcription Factor (SP1))
    Binding Specificity
    • 20
    • 14
    • 12
    • 7
    • 7
    • 7
    • 6
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Middle Region
    Reactivity
    • 95
    • 63
    • 42
    • 9
    • 7
    • 6
    • 5
    • 5
    • 4
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    Human, Mouse, Rat, Cow, Pig, Dog, Goat, Rabbit, Guinea Pig
    Host
    • 96
    • 13
    • 3
    Rabbit
    Clonality
    • 89
    • 23
    Polyclonal
    Conjugate
    • 67
    • 6
    • 4
    • 4
    • 4
    • 4
    • 4
    • 4
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This SP1 antibody is un-conjugated
    Application
    • 90
    • 47
    • 46
    • 38
    • 22
    • 17
    • 14
    • 13
    • 13
    • 8
    • 4
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    Western Blotting (WB)
    Sequence
    TLTPIASAAS IPAGTVTVNA AQLSSMPGLQ TINLSALGTS GIQVHPIQGL
    Predicted Reactivity
    Cow: 100%, Dog: 100%, Goat: 100%, Guinea Pig: 87%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%
    Characteristics
    This is a rabbit polyclonal antibody against SP1. It was validated on Western Blot using a cell lysate as a positive control.
    Purification
    Affinity Purified
    Immunogen
    The immunogen is a synthetic peptide directed towards the middle region of human SP1
    Top Product
    Discover our top product SP1 Primary Antibody
  • Application Notes
    Optimal working dilutions should be determined experimentally by the investigator.
    Comment

    Antigen size: 785 AA

    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    Lot specific
    Buffer
    Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freeze-thaw cycles.
    Storage
    -20 °C
    Storage Comment
    For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
  • Target
    SP1 (Sp1 Transcription Factor (SP1))
    Alternative Name
    SP1 (SP1 Products)
    Synonyms
    fc18h09 antibody, zgc:85950 antibody, wu:fc18h09 antibody, SP1 antibody, 1110003E12Rik antibody, AA450830 antibody, AI845540 antibody, Sp1-1 antibody, sp1 transcription factor antibody, Sp1 transcription factor antibody, Sp1 transcription factor L homeolog antibody, trans-acting transcription factor 1 antibody, sp1 antibody, SP1 antibody, Sp1 antibody, sp1.L antibody
    Background
    SP1 belongs to the Sp1 C2H2-type zinc-finger protein family. It contains 3 C2H2-type zinc fingers. SP1 binds to GC box promoters elements and selectively activates mRNA synthesis from genes that contain functional recognition sites. It can interact with G/C-rich motifs from serotonin receptor promoter.
    Alias Symbols: -
    Protein Interaction Partner: JUN, UBC, HIC1, HDAC1, SP3, TP53, CTNNB1, ARHGAP21, SENP6, C3orf17, USP39, FOXM1, ESR1, DDX5, KIF1A, PPIG, TPI1, TFAP2A, NAP1L1, HDAC2, NUP62, MYC, HIF1A, POU2F1, SMAD3, DDX3X, TBP, SP1, RBL1, Taf4, tat, ESR2, VHL, YY1, CASP7, CASP6, CASP3, HTT, BRCA1, MA
    Protein Size: 785
    Molecular Weight
    81 kDa
    Gene ID
    6667
    NCBI Accession
    NM_138473, NP_612482
    UniProt
    P08047
    Pathways
    Regulation of Lipid Metabolism by PPARalpha, Myometrial Relaxation and Contraction
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