BOP1 antibody (N-Term)

Catalog No. ABIN2773877

Product Details anti-BOP1 Antibody

Target: BOP1 (Block of Proliferation 1 (BOP1))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Horse, Pig, Dog, Rabbit, Saccharomyces cerevisiae, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BOP1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MAGSRGAGRT AAPSVRPEKR RSEPELEPEP EPEPPLLCTS PLSHSTGSDS

Predicted Reactivity: Dog: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 81%, Rat: 100%, Yeast: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against BOP1. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human BOP1

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 746 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-BOP1 antibody (ABIN2773877)

Ewing, Chu, Elisma, Li, Taylor, Climie, McBroom-Cerajewski, Robinson, OConnor, Li, Taylor, Dharsee, Ho, Heilbut, Moore, Zhang, Ornatsky, Bukhman, Ethier, Sheng, Vasilescu, Abu-Farha, Lambert, Duewel et al.: "Large-scale mapping of human protein-protein interactions by mass spectrometry. ..." in: Molecular systems biology, Vol. 3, pp. 89, (2007) (PubMed).

Target Details for BOP1

Target: BOP1 (Block of Proliferation 1 (BOP1))

Alternative Name: BOP1 (BOP1 Products)

Background: BOP1 is the component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
Alias Symbols: KIAA0124
Protein Interaction Partner: FBXW11, UBC, SUMO1, RNF2, C18orf25, SNX5, GORASP2, UGDH, TSNAX, ME1, GTF2A1, GARS, WDR12, PES1, BOP1, NOP58, GNL3, ACIN1, NOP56, RPS7, RPL30, NOP2, NHP2L1, FBL, CAND1, CUL3, SIRT7, SUMO2, KLF10, MYBBP1A, WDR48, ARRB2, ARRB1,
Protein Size: 746

Molecular Weight: 83 kDa

Gene ID: 23246

NCBI Accession: NM_015201, NP_056016

UniProt: Q14137