PTP4A3 antibody (C-Term)

Catalog No. ABIN2773919

Product Details anti-PTP4A3 Antibody

Target: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Binding Specificity: C-Term

Reactivity: Human, Mouse, Rat, Dog, Rabbit, Cow, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PTP4A3 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MKYEDAIQFI RQKRRGAINS KQLTYLEKYR PKQRLRFKDP HTHKTRCCVM

Predicted Reactivity: Cow: 93%, Dog: 86%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 86%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against PTP4A3. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human PTP4A3

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 173 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for PTP4A3

Target: PTP4A3 (Protein Tyrosine Phosphatase Type IVA, Member 3 (PTP4A3))

Alternative Name: PTP4A3 (PTP4A3 Products)

Synonyms: PRL-3 antibody, PRL-R antibody, PRL3 antibody, wu:fc54b05 antibody, wu:fv52d11 antibody, zgc:77109 antibody, prl-3 antibody, prl3 antibody, ptpcaax3 antibody, PTP4A3 antibody, AV088979 antibody, Prl-3 antibody, pPtp4a3 antibody, protein tyrosine phosphatase type IVA, member 3 antibody, protein tyrosine phosphatase type IVA, member 3 L homeolog antibody, protein tyrosine phosphatase 4a3 antibody, PTP4A3 antibody, ptp4a3 antibody, ptp4a3.L antibody, Ptp4a3 antibody

Background: PTP4A3 belongs to a small class of prenylated protein tyrosine phosphatases (PTPs). PTPs are cell signaling molecules that play regulatory roles in a variety of cellular processes. This class of PTPs contains a PTP domain and a characteristic C-terminal prenylation motif. Studies of this class of PTPs in mice demonstrated that they were prenylated proteins in vivo, which suggested their association with cell plasma membrane. Overexpression of this gene in mammalian cells was reported to inhibit angiotensin-II induced cell calcium mobilization and promote cell growth.
Alias Symbols: PRL-3, PRL-R, PRL3
Protein Interaction Partner: ELAVL1, FNTB, FNTA, IPO4, MMS19, NCAPG, SMAP1, SRPRB, XPO5, TTC27, FANCI, ATAD3A, TMEM33, HEATR1, DNAAF5, TNPO2, CNNM3, KIAA1279, RAB3GAP2, NUP188, KIAA0368, XPO7, GCN1L1, SMC2, LRPPRC, UBE4A, AIFM1, USO1, ABCD3, PSMD3, PRPSAP1, POLD1, HNRNPM, MSH2, MCM3,
Protein Size: 173

Molecular Weight: 19 kDa

Gene ID: 11156

NCBI Accession: NM_032611, NP_116000

UniProt: O75365