RABGGTA antibody (N-Term)

Catalog No. ABIN2773937

Product Details anti-RABGGTA Antibody

Target: RABGGTA (Rab Geranylgeranyltransferase, alpha Subunit (RABGGTA))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RABGGTA antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: ELAFTDSLIT RNFSNYSSWH YRSCLLPQLH PQPDSGPQGR LPEDVLLKEL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against RABGGTA. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RABGGTA

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 567 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

References for anti-RABGGTA antibody (ABIN2773937)

Arora, Syed, Machhadieh, McKenna, Kowluru: "Rab-geranylgeranyl transferase regulates glucose-stimulated insulin secretion from pancreatic ? cells." in: Islets, Vol. 4, Issue 5, pp. 354-8, (2012) (PubMed).

Lachance, Cartier, Génier, Munger, Germain, Labrecque, Parent: "Regulation of ?2-adrenergic receptor maturation and anterograde trafficking by an interaction with Rab geranylgeranyltransferase: modulation of Rab geranylgeranylation by the receptor." in: The Journal of biological chemistry, Vol. 286, Issue 47, pp. 40802-13, (2011) (PubMed).

Target Details for RABGGTA

Target: RABGGTA (Rab Geranylgeranyltransferase, alpha Subunit (RABGGTA))

Alternative Name: RABGGTA (RABGGTA Products)

Synonyms: gm antibody, PTAR3 antibody, Rab geranylgeranyl transferase, a subunit antibody, Rab geranylgeranyltransferase alpha subunit antibody, Rab geranylgeranyltransferase, alpha subunit antibody, Rabggta antibody, RABGGTA antibody

Background: RABGGTA belongs to the protein prenyltransferase subunit alpha family and contains 6 PFTA repeats. RABGGTA catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.
Alias Symbols: PTAR3
Protein Interaction Partner: UBC, UBA2, VBP1, SSB, PFDN2, RBMXL2, BMPR2, RAB1A,
Protein Size: 567

Molecular Weight: 65 kDa

Gene ID: 5875

NCBI Accession: NM_182836, NP_878256

UniProt: Q92696