RPL10A antibody (N-Term)

Catalog No. ABIN2774160

Product Details anti-RPL10A Antibody

Target: RPL10A (Ribosomal Protein L10a (RPL10A))

Binding Specificity: N-Term

Reactivity: Human, Mouse, Rat, Cow, Dog, Guinea Pig, Horse, Rabbit, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RPL10A antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MSSKVSRDTL YEAVREVLHG NQRKRRKFLE TVELQISLKN YDPQKDKRFS

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 93%

Characteristics: This is a rabbit polyclonal antibody against RPL10A. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RPL10A

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 217 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for RPL10A

Target: RPL10A (Ribosomal Protein L10a (RPL10A))

Alternative Name: RPL10A (RPL10A Products)

Synonyms: Csa-19 antibody, L10A antibody, NEDD6 antibody, CsA-19 antibody, Nedd6 antibody, wu:fb94f08 antibody, zgc:73082 antibody, zgc:86881 antibody, ribosomal protein L10a antibody, ribosomal protein L10A antibody, ribosomal protein L10a S homeolog antibody, RPL10A antibody, Rpl10a antibody, rpl10a antibody, rpl10a.S antibody

Background: Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L1P family of ribosomal proteins. It is located in the cytoplasm. The expression of this gene is downregulated in the thymus by cyclosporin-A (CsA), an immunosuppressive drug. Studies in mice have shown that the expression of the ribosomal protein L10a gene is downregulated in neural precursor cells during development. This gene previously was referred to as NEDD6 (neural precursor cell expressed, developmentally downregulated 6), but it has been renamed RPL10A (ribosomal protein 10a). As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.
Alias Symbols: Csa-19, NEDD6, L10A
Protein Interaction Partner: RGS17, HUWE1, CEP250, TUBG1, TP53, UBC, MDM2, RNF2, TARDBP, YWHAQ, PAN2, UBL4A, VCAM1, SRPR, ITGA4, FN1, ACTB, ESR1, RPLP0P6, RPL10L, RAD18, RPS27L, RPL23, RPL14, S100A10, RPS28, RPS27A, RPS26, RPS25, RPS24, RPS23, RPS21, RPS20, RPS19, RPS16, RPS15A, RPS1
Protein Size: 217

Molecular Weight: 25 kDa

Gene ID: 4736

NCBI Accession: NM_007104, NP_009035

UniProt: P62906