SENP2 antibody (Middle Region)

Catalog No. ABIN2774191

Product Details anti-SENP2 Antibody

Target: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Cow, Guinea Pig, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SENP2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: RICEILLQYL QDESKTKRNS DLNLLEWTHH SMKPHEIPQQ LNGSDCGMFT

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SENP2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human SENP2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 589 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SENP2

Target: SENP2 (SUMO1/sentrin/SMT3 Specific Peptidase 2 (SENP2))

Alternative Name: SENP2 (SENP2 Products)

Synonyms: 2310007L05Rik antibody, 4930538C18Rik antibody, AI646780 antibody, AW554757 antibody, Smt3ip2 antibody, SuPr-1 antibody, mKIAA1331 antibody, AXAM2 antibody, SMT3IP2 antibody, Axam antibody, SUMO/sentrin specific peptidase 2 antibody, SUMO1/sentrin/SMT3 specific peptidase 2 antibody, Sumo1/sentrin/SMT3 specific peptidase 2 antibody, Senp2 antibody, SENP2 antibody

Background: SUMO1 (UBL1, MIM 601912) is a small ubiquitin-like protein that can be covalently conjugated to other proteins. SENP2 is one of a group of enzymes that process newly synthesized SUMO1 into the conjugatable form and catalyze the deconjugation of SUMO1-containing species.
Alias Symbols: AXAM2, DKFZp762A2316, KIAA1331, SMT3IP2
Protein Interaction Partner: SUMO2, SUMO3, RANGAP1, TMEM239, SYNE4, CCDC155, FUNDC1, AGTRAP, ARL6IP1, TPD52, CDCA5, HNRNPK, APP, TRIM63, SUMO1, HIPK2, IKBKG, DAXX, ELAVL1, NEDD4L, CDK5RAP2, NUP153, AXIN1, PML,
Protein Size: 589

Molecular Weight: 68 kDa

Gene ID: 59343

NCBI Accession: NM_021627, NP_067640

UniProt: Q9HC62

Pathways: Chromatin Binding