IKZF2 antibody (Middle Region)

Catalog No. ABIN2774209

Product Details anti-IKZF2 Antibody

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Dog, Horse, Cow, Guinea Pig, Rabbit, Saccharomyces cerevisiae

Host: Rabbit

Clonality: Polyclonal

Conjugate: This IKZF2 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: EREASPSNSC LDSTDSESSH DDHQSYQGHP ALNPKRKQSP AYMKEDVKAL

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 93%, Rabbit: 100%, Rat: 100%, Yeast: 82%

Characteristics: This is a rabbit polyclonal antibody against IKZF2. It was validated on Western Blot using a cell lysate as a positive control.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human IKZF2

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 526 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for IKZF2

Target: IKZF2 (IKAROS Family Zinc Finger 2 (IKZF2))

Alternative Name: IKZF2 (IKZF2 Products)

Synonyms: ANF1A2 antibody, HELIOS antibody, ZNF1A2 antibody, ZNFN1A2 antibody, helios antibody, znf1a2 antibody, znfn1a1 antibody, znfn1a2 antibody, IKZF2 antibody, MGC159581 antibody, DKFZp469N0319 antibody, A730095J18Rik antibody, Helios antibody, Zfpn1a2 antibody, Znfn1a2 antibody, ikzf2 antibody, znfn1a1-a antibody, IKAROS family zinc finger 2 antibody, si:zfos-1425h8.1 antibody, IKAROS family zinc finger 2 (Helios) antibody, IKAROS family zinc finger 2 L homeolog antibody, IKZF2 antibody, ikzf2 antibody, Ikzf2 antibody, si:zfos-1425h8.1 antibody, ikzf2.L antibody

Background: IKZF2 is associates with Ikaros at centromeric heterochromatin.This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This protein forms homo- or hetero-dimers with other Ikaros family members, and is thought to function predominantly in early hematopoietic development. Multiple transcript variants encoding different isoforms have been found for this gene, but the biological validity of some variants has not been determined.
Alias Symbols: HELIOS, MGC34330, ZNF1A2, ZNFN1A2, ANF1A2
Protein Interaction Partner: LONRF1, CTBP2, AQP1, CTBP1, UBC, HDAC1, HOXA1, NOTCH1, IKZF4, IKZF5, IKZF2, IKZF1, IKZF3, SIN3A, SIN3B, HDAC5, HDAC2, CHD4, HDAC4,
Protein Size: 526

Molecular Weight: 59 kDa

Gene ID: 22807

NCBI Accession: NM_016260, NP_057344

UniProt: Q9UKS7