GABARAPL1 antibody (Middle Region)

Catalog No. ABIN2774240

Product Details anti-GABARAPL1 Antibody

Target: GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))

Binding Specificity: Middle Region

Reactivity: Human, Rat, Mouse, Rabbit, Cow, Dog, Guinea Pig, Horse, Pig, Zebrafish (Danio rerio)

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GABARAPL1 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: VIVEKAPKAR VPDLDKRKYL VPSDLTVGQF YFLIRKRIHL RPEDALFFFV

Predicted Reactivity: Cow: 100%, Dog: 100%, Guinea Pig: 79%, Horse: 79%, Human: 100%, Mouse: 100%, Pig: 100%, Rabbit: 100%, Rat: 100%, Zebrafish: 100%

Characteristics: This is a rabbit polyclonal antibody against GABARAPL1. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of Human GABARAPL1

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for GABARAPL1

Target: GABARAPL1 (GABA(A) Receptor-Associated Protein Like 1 (GABARAPL1))

Alternative Name: GABARAPL1 (GABARAPL1 Products)

Synonyms: gabarapl1 antibody, apg8l antibody, atg8 antibody, atg8l antibody, gec1 antibody, gabarapl1-a antibody, GABARAPL3 antibody, APG8-LIKE antibody, APG8L antibody, ATG8 antibody, ATG8B antibody, ATG8L antibody, GEC1 antibody, Gec1 antibody, 3110025G09Rik antibody, 9130422N19Rik antibody, AI196471 antibody, Apg8l antibody, Atg8l antibody, GECI antibody, GEC-1 antibody, GABA(A) receptor-associated protein like 1 antibody, GABA(A) receptor-associated protein like 1 S homeolog antibody, GABA type A receptor associated protein like 1 antibody, gamma-aminobutyric acid (GABA) A receptor-associated protein-like 1 antibody, gabarapl1 antibody, gabarapl1.S antibody, GABARAPL1 antibody, Gabarapl1 antibody

Background: GABARAPL1 is a Ubiquitin-like modifier that increases cell-surface expression of kappa-type opioid receptor through facilitating anterograde intracellular trafficking of the receptor. it is involved in formation of autophagosomal vacuoles. Whereas LC3s are involved in elongation of the phagophore membrane, the GABARAP/GATE-16 subfamily is essential for a later stage in autophagosome maturation.
Protein Interaction Partner: SQSTM1, KRTAP10-3, KRTAP10-9, KRTAP10-7, FAM134C, FUNDC1, ATG4A, AHNAK2, KBTBD7, SCYL3, TNIP1, CALCOCO2, TBC1D5, UBC, SRPK2, SRPK1, DVL2, MAPK15, STBD1, BNIP3L, ULK1, RB1CC1, ATG13, MAP1LC3A, ATG3, ATG4B, ATG7, NBR1, TBC1D16, TBC1D10A, TBC1D17, TBC1D2, TB
Protein Size: 146

Molecular Weight: 16 kDa

Gene ID: 23710

Pathways: Autophagy