AVPR1B antibody (C-Term)

Catalog No. ABIN2774358

Product Details anti-AVPR1B Antibody

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Binding Specificity: C-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This AVPR1B antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: MRRRLSDGSL SSRHTTLLTR SSCPATLSLS LSLTLSGRPR PEESPRDLEL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against AVPR1B. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 424 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for AVPR1B

Target: AVPR1B (Arginine Vasopressin Receptor 1B (AVPR1B))

Alternative Name: AVPR1B (AVPR1B Products)

Synonyms: LOC443050 antibody, AVPR1B antibody, si:ch211-125a15.3 antibody, AVPR3 antibody, V3/V1b antibody, VIBR antibody, VPR3 antibody, arginine vasopressin receptor 1B antibody, arginine vasopressin receptor 1Ab antibody, AVPR1B antibody, avpr1ab antibody, Avpr1b antibody

Background: The protein encoded by this gene acts as receptor for arginine vasopressin. This receptor belongs to the subfamily of G-protein coupled receptors which includes AVPR1A, V2R and OXT receptors. Its activity is mediated by G proteins which stimulate a phosphatidylinositol-calcium second messenger system. The receptor is primarily located in the anterior pituitary, where it stimulates ACTH release. It is expressed at high levels in ACTH-secreting pituitary adenomas as well as in bronchial carcinoids responsible for the ectopic ACTH syndrome. A spliced antisense transcript of this gene has been reported but its function is not known.
Alias Symbols: AVPR3
Protein Interaction Partner: GRK5, AVP, PRKCA,
Protein Size: 424

Molecular Weight: 47 kDa

Gene ID: 553

NCBI Accession: NM_000707, NP_000698

UniProt: P47901

Pathways: Regulation of Systemic Arterial Blood Pressure by Hormones