SDHC antibody (Middle Region)

Catalog No. ABIN2774372

Product Details anti-SDHC Antibody

Target: SDHC (Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SDHC antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: YSWSLPMAMS ICHRGTGIAL SADVGPRKRP EDSPAIPVWS GCPGSYCVVL

Predicted Reactivity: Human: 100%

Characteristics: This is a rabbit polyclonal antibody against SDHC. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 150 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SDHC

Target: SDHC (Succinate Dehydrogenase Complex, Subunit C, Integral Membrane Protein, 15kDa (SDHC))

Alternative Name: SDHC (SDHC Products)

Synonyms: SDHC antibody, 0610010E03Rik antibody, AI316496 antibody, AU019277 antibody, CYB560 antibody, CYBL antibody, PGL3 antibody, QPS1 antibody, SDH3 antibody, succinate dehydrogenase complex subunit C antibody, succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa antibody, succinate dehydrogenase complex, subunit C, integral membrane protein antibody, SDHC antibody, sdhc antibody, SdhC antibody, Sdhc antibody

Background: This gene encodes one of four nuclear-encoded subunits that comprise succinate dehydrogenase, also known as mitochondrial complex II, a key enzyme complex of the tricarboxylic acid cycle and aerobic respiratory chains of mitochondria. The encoded protein is one of two integral membrane proteins that anchor other subunits of the complex, which form the catalytic core, to the inner mitochondrial membrane. Several related pseudogenes are located in different genomic regions. Mutations in this gene have been associated with paragangliomas. Alternatively spliced transcript variants encoding different isoforms have been described.
Alias Symbols: CYB560, CYBL, PGL3, QPS1, SDH3
Protein Interaction Partner: MDM2, UBC, XRCC6, ARHGDIA,
Protein Size: 150

Molecular Weight: 17 kDa

Gene ID: 6391

NCBI Accession: NM_001035511, NP_001030588