SEC62 antibody (Middle Region)

Catalog No. ABIN2774392

Product Details anti-SEC62 Antibody

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Guinea Pig, Cow, Dog, Horse, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SEC62 antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KYDKDIKKEK DKGKAESGKE EDKKSKKENI KDEKTKKEKE KKKDGEKEES

Predicted Reactivity: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 86%, Rabbit: 93%, Rat: 100%

Characteristics: This is a rabbit polyclonal antibody against SEC62. It was validated on Western Blot.

Purification: Affinity Purified

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 399 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for SEC62

Target: SEC62 (TLOC1) (Translocation Protein 1 (TLOC1))

Alternative Name: SEC62 (TLOC1 Products)

Synonyms: tloc1 antibody, TLOC1 antibody, wu:fb57b06 antibody, zgc:114073 antibody, Dtrp1 antibody, HTP1 antibody, TP-1 antibody, 3100002M17Rik antibody, AI844545 antibody, AW545092 antibody, Tloc1 antibody, Ab2-292 antibody, SEC62 homolog, preprotein translocation factor S homeolog antibody, SEC62 homolog, preprotein translocation factor antibody, membrane unit of ER protein translocation apparatus antibody, SEC62 homolog (S. cerevisiae) antibody, sec62.S antibody, SEC62 antibody, sec62 antibody, Sec62 antibody

Background: The Sec61 complex is the central component of the protein translocation apparatus of the endoplasmic reticulum (ER) membrane. The protein encoded by this gene and SEC63 protein are found to be associated with ribosome-free SEC61 complex. It is speculated that Sec61-Sec62-Sec63 may perform post-translational protein translocation into the ER. The Sec61-Sec62-Sec63 complex might also perform the backward transport of ER proteins that are subject to the ubiquitin-proteasome-dependent degradation pathway. The encoded protein is an integral membrane protein located in the rough ER.
Alias Symbols: Dtrp1, FLJ32803, HTP1, TLOC1, TP-1
Protein Interaction Partner: UBC, ZNF24, SEC62, env, GLUD1, CIC, SEC63,
Protein Size: 399

Molecular Weight: 46 kDa

Gene ID: 7095

NCBI Accession: NM_003262, NP_003253

UniProt: Q99442